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Table of Contents
Vol. 22, No. 6, 2007
Issue release date: October 2007
Section title: Paper
Fetal Diagn Ther 2007;22:435–439
(DOI:10.1159/000106350)

Postnatal Chest Wall Deformities after Fetal Thoracoamniotic Shunting for Congenital Cystic Adenomatoid Malformation

Merchant A.M. · Peranteau W. · Wilson R.D. · Johnson M.P. · Bebbington M.W. · Hedrick H.L. · Flake A.W. · Adzick N.S.
Center for Fetal Diagnosis and Treatment, Children’s Hospital of Philadelphia, and Departments of Surgery and Obstetrics/Gynecology, University of Pennsylvania, Philadelphia, Pa., USA

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Article / Publication Details

First-Page Preview
Abstract of Paper

Received: 7/24/2006
Accepted: 8/28/2006
Published online: 7/24/2007
Issue release date: October 2007

Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 3

ISSN: 1015-3837 (Print)
eISSN: 1421-9964 (Online)

For additional information: http://www.karger.com/FDT

Abstract

Objectives: Large macrocystic congenital cystic adenomatoid malformations (CCAMs) can be treated with thoracoamniotic (TA) shunting to reduce CCAM volume. Two CCAM fetuses treated with TA shunt had postnatal radiographic rib deformities. Study Design: Retrospective review of prenatal TA shunting for large macrocystic CCAMs evaluated for the presence of rib deformities. Comparison groups not eligible for TA shunting included nonshunted CCAMs resected postnatally (group A) and size-matched nonshunted CCAMs resected postnatally (group B). Results: Chest wall abnormalities were identified in 77% of newborns ranging from severe concavity and fractures (in two fetuses shunted at 18 and 20 weeks of gestation) to rib thinning compared to comparison groups A and B. The severity of chest wall deformity correlated with earlier gestational age at shunting. Conclusions: TA shunting at less than 21 weeks of gestational age may result in postnatal chest wall deformity. This observation should be discussed during counseling for this procedure.

© 2007 S. Karger AG, Basel


  

Author Contacts

R.D. Wilson, MD
Center for Fetal Diagnosis and Treatment, Children’s Hospital of Philadelphia
34th Street and Civic Center Boulevard, 5th Floor Wood Building
Philadelphia, PA 19104-4399 (USA)
Tel. +1 215 590 4016, Fax +1 215 490 2447, E-Mail wilsond@email.chop.edu

  

Article Information

Received: July 24, 2006
Accepted after revision: August 28, 2006
Published online: July 24, 2007
Number of Print Pages : 5
Number of Figures : 2, Number of Tables : 3, Number of References : 12

  

Publication Details

Fetal Diagnosis and Therapy (Clinical Advances and Basic Research)

Vol. 22, No. 6, Year 2007 (Cover Date: October 2007)

Journal Editor: Holzgreve, W. (Basel)
ISSN: 1015–3837 (print), 1421–9964 (Online)

For additional information: http://www.karger.com/FDT


Article / Publication Details

First-Page Preview
Abstract of Paper

Received: 7/24/2006
Accepted: 8/28/2006
Published online: 7/24/2007
Issue release date: October 2007

Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 3

ISSN: 1015-3837 (Print)
eISSN: 1421-9964 (Online)

For additional information: http://www.karger.com/FDT


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