Association of Ultrasound Findings with Decision to Continue Down Syndrome PregnanciesPerry S. · Woodall A.L. · Pressman E.K.
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Rochester, Rochester, N.Y., USA
Objective: To evaluate the association of ultrasound findings and other factors with the decision to terminate trisomy-21-affected pregnancies. Methods: We performed a retrospective analysis of trisomy-21-affected pregnancies diagnosed prior to 24 weeks’ gestation. Data were collected on maternal age, indications for prenatal diagnosis, gestational age at diagnosis, marital status, race, parity and ultrasound findings. Logistic regression, χ2, t test and Fishers exact test were used for statistical analysis. Results: Fifty-nine pregnancies were identified with a termination rate of 72.9%. Termination rates were significantly lower in patients with major (50%) or minor (64%) ultrasound abnormalities than in patients with normal ultrasound exams (92%), p = 0.026 and 0.022, respectively. Patients who chose terminations were older (36.1 vs. 32.3), but this did not reach statistical significance (p = 0.059). Conclusion: Patients with abnormal ultrasound results were more likely to continue a trisomy 21 pregnancy.
Eva K. Pressman, MD
Strong Memorial Hospital, Box 668
601 Elmwood Avenue
Rochester, NY 14642 (USA)
Tel. +1 585 275 7480, Fax +1 585 256 1416, E-Mail firstname.lastname@example.org
Number of Print Pages : 4
Number of Figures : 2, Number of Tables : 3, Number of References : 5
Vol. 10, No. 4, Year 2007 (Cover Date: September 2007)
Journal Editor: ten Kate, L.P. (Amsterdam)
ISSN: 1422–2795 (print), 1422–2833 (Online)
For additional information: http://www.karger.com/CMG