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Mild Cognitive Impairment in General Practice: Age-Specific Prevalence and Correlate Results from the German Study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe)Luck T.a · Riedel-Heller S.G.a · Kaduszkiewicz H.b · Bickel H.c · Jessen F.d · Pentzek M.e · Wiese B.f · Koelsch H.d · van den Bussche H.b · Abholz H.-H.e · Moesch E.c · Gorfer S.g · Angermeyer M.C.a · Maier W.d · Weyerer S.g
aDepartment of Psychiatry, University of Leipzig, Leipzig, bInstitute for General Medicine, University Medical Centre, Hamburg, cDepartment of Psychiatry, Technical University of Munich, Munich, dDepartment of Psychiatry, University of Bonn, Bonn, eDepartment of General Practice, University Medical Centre, Düsseldorf, fInstitute for Biometrics, Hannover Medical School, Hannover, and gCentral Institute for Mental Health, Mannheim, Germany Corresponding Author
Dipl.-Psych. Tobias Luck
Department of Psychiatry, University of Leipzig
DE–04317 Leipzig (Germany)
Tel. +49 341 972 4568, Fax +49 341 972 4539, E-Mail email@example.com
Background: Although mild cognitive impairment (MCI) represents a high-risk factor for developing dementia, little is known about the prevalence of MCI among patients of general practitioners (GPs). Aims: Estimation of age-specific prevalence for original and modified concepts of MCI and their association with sociodemographic, medical and genetic (apoE Ε4 genotype) factors among patients of GPs. Methods: A GP practice sample of 3,327 individuals aged 75+ was assessed by structured clinical interviews. Results: Prevalence was 15.4% (95% CI = 14.1–16.6) for original and 25.2% (95% CI = 23.7–26.7) for modified MCI. Rates increased significantly with older age. Positive associations were found for apoE Ε4 allele, vascular diseases and depressive symptoms. Conclusion: MCI is frequent in elderly patients of GPs. GPs have a key position in secondary prevention and care of incipient cognitive deterioration up to the diagnosis of dementia.
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