Young-Onset Parkinson’s Disease: Hospital Utilization and Medical Comorbidity in a Nationwide SurveyLouis E.D. · Henchcliffe C. · Bateman B.T. · Schumacher C.
aGH Sergievsky Center, bDepartment of Neurology and cthe Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, and dDepartment of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, N.Y., USA
Background/Aims: 10% of Parkinson’s disease (PD) patients have young-onset PD (YOPD). We compared YOPD patients to control patients in terms of hospital utilization and outcomes and medical comorbidities during hospitalization. Methods: The Nationwide Inpatient Sample (NIS) provides yearly data on hospital admissions and discharges from approximately 1,000 hospitals. NIS data sets (1998–2003) were used to identify persons aged 18–40 years, including 714 PD patients and 2,007 randomly selected control patients (1:3 matching). Results: Hospital length of stay (p < 0.001) and number of discharge diagnoses (p < 0.001) were higher in PD patients than controls. PD patients were more likely than controls to be discharged to a short-term hospital (odds ratio, OR, 2.23, 95% confidence interval, CI, 1.30–3.84, p = 0.004) or a skilled nursing facility (OR 4.14, 95% CI 3.06–5.61, p < 0.001); 20.4% required transfer to a short-term hospital or another facility. The most common discharge Diagnosis-Related Group code in PD patients was psychosis (23% of patients) whereas pneumonia and hip or pelvic fractures were not associated with PD. Conclusions: YOPD patients had greater healthcare utilization and hospital morbidity than controls. Upon discharge, 1 in 5 required transfer to a short-term hospital or another facility. Psychosis was the most common comorbidity whereas several comorbidities associated with older PD patients were not common.
Dr. Elan Louis
Unit 198, Neurological Institute
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New York, NY 10032 (USA)
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Published online: September 24, 2007
Number of Print Pages : 5
Number of Figures : 0, Number of Tables : 3, Number of References : 17
Vol. 29, No. 1-2, Year 2007 (Cover Date: November 2007)
Journal Editor: Román, G.C. (San Antonio, Tex.)
ISSN: 0251–5350 (Print), eISSN: 1423–0208 (Online)
For additional information: http://www.karger.com/NED