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Vol. 216, No. 1, 2008
Issue release date: November 2007
Section title: Case Report
Dermatology 2008;216:76–80
(DOI:10.1159/000109363)

Azo Pigments and a Basal Cell Carcinoma at the Thumb

Engel E. · Ulrich H. · Vasold R. · König B. · Landthaler M. · Süttinger R. · Bäumler W.
aDepartment of Dermatology and bInstitute of Organic Chemistry, University of Regensburg, Regensburg, cBASF AG, Ludwigshafen, Germany

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 4/9/2007
Accepted: 5/30/2007
Published online: 11/28/2007

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Basal cell carcinoma is the most common malignant neoplasm of the skin, whereas the localization at the nail unit is very rare. We report the case of a 58-year-old patient with a periungual basal cell carcinoma at the thumb. The specific feature of the reported case is the frequent exposure to fishing baits that the patient had stained with an unknown colorant. The use of chromatography, mass spectrometry and infrared spectroscopy revealed the colorant as the azo pigment Solvent Red 8. Solvent Red 8 is a widespread synthetic azo pigment that is applied to stain consumer products. Compounds such as Solvent Red 8 can be cleaved to carcinogenic amines under, for example, light exposure, in particular after incorporation into the human body. As a result of the frequent skin contact to this azo pigment, this hazard compound might have induced the basal cell carcinoma in our patient.


  

Author Contacts

Wolfgang Bäumler, PhD, Ass. Prof.
Department of Dermatology, University of Regensburg
DE–93042 Regensburg (Germany)
Tel. +49 941 944 9607, Fax +49 941 944 9647
E-Mail baeumler.wolfgang@klinik.uni-regensburg.de

  

Article Information

Received: April 9, 2007
Accepted: May 30, 2007
Number of Print Pages : 5
Number of Figures : 3, Number of Tables : 0, Number of References : 15

  

Publication Details

Dermatology

Vol. 216, No. 1, Year 2008 (Cover Date: November 2007)

Journal Editor: Saurat, J.-H. (Geneva)
ISSN: 1018–8665 (print), 1421–9832 (Online)

For additional information: http://www.karger.com/DRM


Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 4/9/2007
Accepted: 5/30/2007
Published online: 11/28/2007

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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