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Table of Contents
Vol. 26, No. 1, 2008
Issue release date: December 2007
Section title: Review
Dig Dis 2008;26:40–44
(DOI:10.1159/000109385)

Intragastric Balloon Treatment for Obesity: What Does It Really Offer?

Mathus-Vliegen E.M.H.
Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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Article / Publication Details

First-Page Preview
Abstract of Review

Published online: 2/15/2008
Issue release date: December 2007

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 1

ISSN: 0257-2753 (Print)
eISSN: 1421-9875 (Online)

For additional information: http://www.karger.com/DDI

Abstract

Obesity is a chronic metabolic disorder with considerable health risks, which can be approved by a sustained modest weight loss. This can be achieved by medical treatment through behavioral therapy, diet, exercise and pharmacotherapy. Surgery is often needed for the severely obese. Intragastric balloon treatment stands in between, being more drastic than medical treatment but less invasive than surgery. In the light of the high premature deflation rate and the high incidence of gastric ulcers, a safer balloon had to be awaited, constructed according to predefined criteria. This new balloon (BioEnterics® Intragastric Balloon™) promoted a weight loss of 5–9 BMI units in 6 months with an impressive improvement of obesity-associated comorbidities. A weight regain of 25–40% has to be considered in a 1-year balloon-free follow-up period. A failure rate of 15% was observed in studies that defined a successful weight loss. With respect to safety, there was no mortality. Gastrointestinal complications, mainly consisting of esophagitis, were present in 5.5%. Intolerance of the balloon resulted in its removal in 7%. Balloons deflated in 8% with an uneventful outcome in all except 5 patients, who had to be operated. Balloon treatment is a valuable method, but nonresponse, intolerance and weight regain have to be taken into account.

© 2008 S. Karger AG, Basel


  

Author Contacts

Prof. Dr. E.M.H. Mathus-Vliegen
Department of Gastroenterology and Hepatology, Academic Medical Centre
PO Box 22 700
NL–1100 DE Amsterdam (The Netherlands)
Tel. +31 20 566 2707, Fax +31 20 691 7033, E-Mail e.mathus-vliegen@amc.uva.nl

  

Article Information

Published online: NIL
Number of Print Pages : 5
Number of Figures : 0, Number of Tables : 1, Number of References : 40

  

Publication Details

Digestive Diseases (Clinical Reviews)

Vol. 26, No. 1, Year 2008 (Cover Date: December 2007)

Journal Editor: Malfertheiner, P. (Magdeburg)
ISSN: 0257–2753 (Print), eISSN: 1421–9875 (Online)

For additional information: http://www.karger.com/DDI


Article / Publication Details

First-Page Preview
Abstract of Review

Published online: 2/15/2008
Issue release date: December 2007

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 1

ISSN: 0257-2753 (Print)
eISSN: 1421-9875 (Online)

For additional information: http://www.karger.com/DDI


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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