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Vol. 1, No. 1, 2007
Issue release date: 2007
Section title: Published: December 2007

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Case Rep Gastroenterol 2007;1:144–151
(DOI:10.1159/000111173)

Kayexalate Intake (in Sorbitol) and Jejunal Diverticulitis, a Causative Role or an Innocent Bystander?

Pusztaszeri M. · Christodoulou M. · Proietti S. · Seelentag W.
Departments of aPathology, bSurgery and cRadiology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland

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Abstract

Small intestine diverticulosis is a rare entity that is asymptomatic in the majority of cases. However, it may cause serious complications, such as infection, hemorrhage, intestinal obstruction and diverticulitis. Kayexalate (sodium polystyrene sulfonate) in sorbitol has been associated with colonic necrosis and less frequently with upper gastrointestinal injuries in a subset of uremic patients treated for hyperkalemia. We report a case of jejunal diverticulosis with mucosal injury and diverticulitis in a uremic patient treated with Kayexalate and discuss the potential role of Kayexalate in the pathogenesis of diverticulitis.


  

Author Contacts

Marc Pusztaszeri
Institute of Pathology, Centre Hospitalier Universitaire Vaudois (CHUV)
Rue du Bugnon 25
CH–1011 Lausanne (Switzerland)
Tel. +41 21 314 29 54, Fax +41 21 314 71 15, E-Mail Marc.Pusztaszeri@chuv.ch

  

Article Information

Published online: December 4, 2007
Number of Print Pages : 8
Number of Figures : 3, Number of Tables : 0, Number of References : 15

  

Publication Details

Case Reports in Gastroenterology

Vol. 1, No. 1, Year 2007 (Cover Date: December 2007)

Journal Editor: Urrutia, R. (Rochester, Minn.)
ISSN: NIL (print), 1662–0631 (Online)

For additional information: http://www.karger.com/CRG


Article / Publication Details

First-Page Preview
Abstract of Published: December 2007

Published online: 12/4/2007

Number of Print Pages: 8
Number of Figures: 3
Number of Tables: 0

ISSN: (Print)
eISSN: 1662-0631 (Online)

For additional information: http://www.karger.com/CRG


Open Access License / Drug Dosage

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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