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Table of Contents
Vol. 216, No. 2, 2008
Issue release date: January 2008
Section title: Case Report
Dermatology 2008;216:163–165
(DOI:10.1159/000111515)

Treatment of Idiopathic Pyoderma Gangrenosum with Infliximab: Induction Dosing Regimen or On-Demand Therapy?

Adışen E. · Öztaş M. · Gürer M.A.
Department of Dermatology, Gazi University Faculty of Medicine, Ankara, Turkey

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: March 26, 2007
Accepted: June 20, 2007
Published online: January 23, 2008
Issue release date: January 2008

Number of Print Pages: 3
Number of Figures: 2
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Pyoderma gangrenosum is an ulcerative skin disease of unknown origin. Recently tumor necrosis factor α inhibitors have been gaining attention in the treatment of recalcitrant pyoderma gangrenosum. However, there is a lack of an optimal dosing strategy in the published literature about the treatment of idiopathic pyoderma gangrenosum, and this is responsible for substantially different treatment strategies. Therefore, it is necessary to report experiences in this patient population in order to develop an optimal dosing strategy and to clarify whether regularly scheduled or on-demand therapy is suitable for idiopathic pyoderma gangrenosum. Herein we report a recalcitrant case of an idiopathic pyoderma gangrenosum treated successfully with a dosing regimen similar to the one that has been used in psoriasis. By doing so, we were capable of controlling the disease and improving the quality of life in our patient.

© 2008 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: March 26, 2007
Accepted: June 20, 2007
Published online: January 23, 2008
Issue release date: January 2008

Number of Print Pages: 3
Number of Figures: 2
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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