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Vol. 25, No. 1, 2008
Issue release date: December 2007
Section title: Original Research Article
Dement Geriatr Cogn Disord 2008;25:81–87
(DOI:10.1159/000111694)

Relationship between Measures of Dementia Severity and Observation of Daily Life Functioning as Measured with the Assessment of Motor and Process Skills (AMPS)

Bouwens S.F.M. · van Heugten C.M. · Aalten P. · Wolfs C.A.G. · Baarends E.M. · van Menxel D.A.J. · Verhey F.R.J.
aSchool for Mental Health and Neuroscience/Alzheimer Centrum Limburg, Department of Psychiatry and Neuropsychology, Maastricht University, and bDepartment of Occupational Therapy, azM, University Hospital Maastricht, Maastricht, cCentre of Excellence in Rehabilitation Medicine, Utrecht, dDepartment of Occupational Therapy, Zuyd University, Heerlen, The Netherlands

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Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Accepted: 9/24/2007
Published online: 11/28/2007

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 4

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM

Abstract

Background: Cognitive impairment is mostly regarded as the core symptom of dementia, but several other domains (such as daily functioning) are equally relevant to assess the severity of dementia. The relationship between these domains is unclear. The Assessment of Motor and Process Skills (AMPS) is a relatively unexplored instrument in people with dementia, measuring severity by direct observation. Objective: To study the relationship between the AMPS and scores on several commonly used outcome measures for the assessment of dementia severity, and to examine the possible influence of neuropsychiatric symptoms on these relationships in patients with cognitive disorders. Methods: Cross-sectional data of 118 patients with cognitive disorders were used; data on cognition (Mini-Mental State Examination, MMSE; CAMCOG), global severity (Global Deterioration Scale, GDS), daily life functioning (Instrumental Activities of Daily Living, IADL), and neuropsychiatric symptoms (Neuropsychiatric Inventory, NPI) were collected and analyzed using correlation and regression analyses. Different combinations of the severity measures were tested for their ability to predict the AMPS process ability scores. Results: Scores on the MMSE, CAMCOG and GDS were moderately associated with the AMPS process ability score. These measures explained between 27 and 44% of the variance in the AMPS score. The presence of apathy influenced the association between the cognitive measures and the AMPS score. Conclusion: Commonly used measures of dementia severity are only moderately associated with observation of performance on daily activities. This underlines the need for direct observation of daily activities in dementia patients. This relationship between several approaches of assessing dementia severity needs further study.


  

Author Contacts

Prof. F.R.J. Verhey, MD, PhD, Professor of Neuropsychiatry and Old Age Psychiatry
University Hospital of Maastricht/Alzheimer Centre Limburg
PO Box 5800
NL–6202 AZ Maastricht (The Netherlands)
Tel. +31 43 38 74175, Fax +31 43 38 75444, E-Mail f.verhey@np.unimaas.nl

  

Article Information

Accepted: September 24, 2007
Published online: November 28, 2007
Number of Print Pages : 7
Number of Figures : 0, Number of Tables : 4, Number of References : 34

  

Publication Details

Dementia and Geriatric Cognitive Disorders

Vol. 25, No. 1, Year 2008 (Cover Date: December 2007)

Journal Editor: Chan-Palay, V. (New York, N.Y.)
ISSN: 1420–8008 (print), 1421–9824 (Online)

For additional information: http://www.karger.com/DEM


Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Accepted: 9/24/2007
Published online: 11/28/2007

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 4

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM


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