Journal Mobile Options
Table of Contents
Vol. 6, No. 6, 1983/1984
Issue release date: 1983/1984
Section title: Original Papers
Dev Neurosci 1983–84;6:345–355
(DOI:10.1159/000112361)

In vivo Phosphorylation of Myelin Basic Proteins in Developing Mouse Brain: Evidence that Phosphorylation Is an Early Event in Myelin Formation

Ulmer J.B. · Braun P.E.
Department of Biochemistry, McGill University, Montreal, Canada

Do you have an account?

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger (new!)
  • Unrestricted printing, no saving restrictions for personal use
  • Reduced rates with a PPV account
read more

Direct: USD 9.00
Account: USD 8.00

Select

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply

Rental: USD 8.50
Cloud: USD 20.00

Select

Subscribe

  • Access to all articles of the subscribed year(s) guaranteed for 5 years
  • Unlimited re-access via Subscriber Login or MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

Subcription rates


Select


Article / Publication Details

First-Page Preview
Abstract of Original Papers

Received: 6/28/1984
Accepted: 1/1/1985
Published online: 6/29/2009
Issue release date: 1983/1984

Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0

ISSN: 0378-5866 (Print)
eISSN: 1421-9859 (Online)

For additional information: http://www.karger.com/DNE

Abstract

Myelin basic proteins (MBPs) can be detected in 5-day mouse brain, even though there is very little myelin present. In addition to the 4 MBP components (with molecular weights of 14, 17, 18.5 and 21.5 kilodaltons), that are commonly observed, other larger MBP-related polypeptides are also present. We have investigated the possibility of MBP phosphorylation at early stages of development in order to establish the point at which this modification occurs in the assembly of myelin. In vivo isotope studies show that in the 5-day mouse brain 14-, 17-, 18.5- and 21.5- kilodalton MBPs are phosphorylated and that they may be present in an immature form of myelin. Larger MBP-related proteins with a molecular weight of 35 and 42 kilodaltons are also phosphorylated but appear to be present mostly in nonmyelin structures or compartments.

© 1983 S. Karger AG, Basel


  

Author Contacts

Dr. P.E. Braun, Department of Biochemistry, McGill University, 3655 Drummond Street, Montreal, Que. H3G 1Y6 (Canada)

  

Article Information

Received: June 28, 1984
Accepted: January 1, 1985
Number of Print Pages : 11

  

Publication Details

Developmental Neuroscience

Vol. 6, No. 6, Year 1983/1984 (Cover Date: 1983/1984)

Journal Editor: Campagnoni, A.T. (Los Angeles, Calif.)
ISSN: 0378–5866 (print), 1421–9859 (Online)

For additional information: http://www.karger.com/DNE


Article / Publication Details

First-Page Preview
Abstract of Original Papers

Received: 6/28/1984
Accepted: 1/1/1985
Published online: 6/29/2009
Issue release date: 1983/1984

Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0

ISSN: 0378-5866 (Print)
eISSN: 1421-9859 (Online)

For additional information: http://www.karger.com/DNE


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.