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Vol. 216, No. 4, 2008
Issue release date: May 2008
Section title: Case Report
Dermatology 2008;216:337–340
(DOI:10.1159/000115968)

Induction of Benign Symmetric Lipomatosis (Launois-Bensaude Syndrome) in a Female Patient after Liver Transplantation

Goetze S. · Hommann M. · Elsner P. · Kaatz M.
Departments of aDermatology and bGeneral and Visceral Surgery, Friedrich Schiller University, Jena, Germany

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 6/21/2007
Accepted: 10/10/2007
Published online: 2/8/2008

Number of Print Pages: 4
Number of Figures: 3
Number of Tables: 1

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Benign symmetric lipomatosis, also known as Madelung’s disease or Launois-Bensaude syndrome, is a rare disease, the etiology of which is still unknown. The presence of multiple, symmetric, nonencapsulated lipomatous masses in the face, neck, upper arms and upper trunk is typical. Until now many causes have been discussed among which liver dysfunctions are described frequently. In up to 90% of patients, alcoholism is observed. In our case the Launois-Bensaude syndrome developed after liver transplantation in a 49-year-old female patient suffering from decompensated cirrhosis (Child-Pugh C score: 12 points). Shortly after the transplantation a slow progress in tissue-building appeared on both upper arms, cervical areas as well as in the face. During postsurgical prednisolone therapy, a massive increase in fluid in the tissue developed, which led to a discontinuation of this therapy regimen. In the further course there was an increase in weight of 20 kg. As far as we know, this case is the first description of the induction of a Launois-Bensaude syndrome following liver transplantation.


  

Author Contacts

Steven Goetze, MD
Department of Dermatology, Friedrich Schiller University
Erfurter Strasse 35
DE–07740 Jena (Germany)
Tel. +49 3641 937 305, Fax +49 3641 937 403, E-Mail steven.goetze@derma.uni-jena.de

  

Article Information

Received: June 21, 2007
Accepted: October 10, 2007
Published online: February 12, 2008
Number of Print Pages : 4
Number of Figures : 3, Number of Tables : 1, Number of References : 17

  

Publication Details

Dermatology

Vol. 216, No. 4, Year 2008 (Cover Date: May 2008)

Journal Editor: Saurat, J.-H. (Geneva)
ISSN: 1018–8665 (Print), eISSN: 1421–9832 (Online)

For additional information: http://www.karger.com/DRM


Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 6/21/2007
Accepted: 10/10/2007
Published online: 2/8/2008

Number of Print Pages: 4
Number of Figures: 3
Number of Tables: 1

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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