Login to MyKarger

New to MyKarger? Click here to sign up.



Login with Facebook

Forgot your password?

Authors, Editors, Reviewers

For Manuscript Submission, Check or Review Login please go to Submission Websites List.

Submission Websites List

Institutional Login
(Shibboleth or Open Athens)

For the academic login, please select your country in the dropdown list. You will be redirected to verify your credentials.

Original Research Article

Free Access

Memory Decline and Depressive Symptoms in a Nationally Representative Sample of Older Adults: The Health and Retirement Study (1998–2004)

González H.M.a-c · Bowen M.E.a · Fisher G.G.c

Author affiliations

aInstitute of Gerontology and bDepartment of Medicine and Public Health Sciences, Wayne State University, Detroit, Mich., and cInstitute of Social Research, University of Michigan, Ann Arbor, Mich., USA

Corresponding Author

Hector M. González

Institute of Gerontology, Wayne State University

87 East Ferry Street, 226 Knapp Building

Detroit, MI 48202 (USA)

Tel. +1 313 577 2297, Fax +1 313 875 0127, E-Mail hmgonzalez@med.wayne.edu

Related Articles for ""

Dement Geriatr Cogn Disord 2008;25:266–271

Do you have an account?

Login Information





Contact Information










I have read the Karger Terms and Conditions and agree.



Abstract

Background/Aims: Inconsistencies in the relationship between depression and cognitive decline may exist because the expected cognitive domains at risk have not been specified in previous study designs. We aimed to examine the relationship between depressive symptoms and verbal episodic memory functioning over time. Methods: Data from a prospective cohort study (Health and Retirement Study; 1998–2004; n = 18,465), a multistage national probability sample of older adults in the United States, were analyzed. Verbal learning and memory of a 10-word list learning task were the main outcomes. Depressive symptoms (Center for Epidemiologic Studies – Depression Scale) constituted the main predictor. Results: Depressive symptoms were associated with significantly lower immediate (–0.05; p < 0.001) and delayed (–0.06; p < 0.001) word list recall scores after controlling for demographics and baseline and time-varying cardiovascular disease risks and diseases. Conclusions: In this US national study of older adults, elevated depressive symptoms were associated with declines in episodic learning and memory over time. These associations were little affected by the demographic or medical conditions considered in this study. The results suggest that learning and memory decline may be a long-term feature associated with depressive symptoms among the nation’s older adult population.

© 2008 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Accepted: January 12, 2007
Published online: February 13, 2008
Issue release date: March 2008

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 3

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM


Copyright / Drug Dosage / Disclaimer

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.