Thirty-two patients with hemifacial spasm were treated with 61 botulinum toxin (BT) injections. Some patients had post-BT lower facial paresis (LFP+ group) while others did not suffer this side effect (LFP- group). Abnormal electromyography (EMG) recordings were more frequent in the LFP+ group (6/11) than in the LFP- group (3/21; p < 0.05). This result suggests that an EMG performed before any BT injection could detect the patients with a higher risk for this side effect. The first dose of BT might be lowered in such cases.
Olivier Rascol, Service de Pharmacologic Clinique, Hôpital Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex (France)
Received: October 20, 1993
Accepted: March 9, 1994
Published online: February 12, 2008
Number of Print Pages : 3
Vol. 35, No. 1, Year 1995 (Cover Date: 1995)
Journal Editor: Bogousslavsky, J. (Montreux)
ISSN: 0014–3022 (Print), eISSN: 1421–9913 (Online)
For additional information: http://www.karger.com/ENE
Copyright / Drug Dosage
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