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Vol. 14, No. 2, 1985
Issue release date: 1985
Section title: Biological Psychiatry
Neuropsychobiology 1985;14:67–74
(DOI:10.1159/000118207)

Biological Correlations of Suicide and Aggressivity in Major Depressions (with Melancholia): 5-Hydroxyindoleacetic Acid and Cortisol in Cerebral Spinal Fluid, Dexamethasone Suppression Test and Therapeutic Response to 5-Hydroxytryptophan

López-Ibor, Jr. J.J. · Saiz-Ruiz J. · Perez De los Cobos J.C.
Centro Ramón y Cajal, Madrid, Spain

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Article / Publication Details

First-Page Preview
Abstract of Biological Psychiatry

Published online: 2/19/2008
Issue release date: 1985

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: http://www.karger.com/NPS

Abstract

5-Hydroxyindoleacetic acid (5-HIAA) and cortisol in cerebrospinal fluid (CSF), response of the dexamethasone suppression test (DST) and the clinical response to treatment with 5-hydroxytryptophan (5-HTp) plus carbidopa were studied in a group of 21 depressed inpatients (major depression with melancholia) in order to correlate biological findings with psychopathologicalones. A positive correlation was found between strong suicidal thoughts, suicidal attempts and self-aggressivity and low concentration of 5-HIAA in CSF and a less significant but still positive correlation with abnormal DST response and with clinical response to the treatment.

© 1985 S. Karger AG, Basel


  

Author Contacts

Juan José López-Ibor, Jr., Avenida Nueva Zelanda 44, E-28035 Madrid (Spain)

  

Article Information

Published online: NIL
Number of Print Pages : 8

  

Publication Details

Neuropsychobiology (International Journal of Experimental and Clinical Research in Biological Psychiatry, Pharmacopsychiatry, Biological Psychology/Pharmacopsychology and Pharmacoelectroencephalography)

Vol. 14, No. 2, Year 1985 (Cover Date: 1985)

Journal Editor: Strik, W. (Bern)
ISSN: 0302–282X (Print), eISSN: 1423–0224 (Online)

For additional information: http://www.karger.com/NPS


Article / Publication Details

First-Page Preview
Abstract of Biological Psychiatry

Published online: 2/19/2008
Issue release date: 1985

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: http://www.karger.com/NPS


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