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Table of Contents
Vol. 27, No. 4, 1993
Issue release date: 1993
Section title: Biological Psychiatry
Neuropsychobiology 1993;27:193–198
(DOI:10.1159/000118980)

Rapid Cycling Patients: Conceptual and Etiological Factors

Ananth J.a · Wohl M.a · Ranganath V.b · Beshay M.b
aUCLA and Harbor UCLA Medical Center, Torrance, Calif., USA; bKing Drew Medical Center, Compton, Calif., USA

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Article / Publication Details

First-Page Preview
Abstract of Biological Psychiatry

Published online: February 22, 2008
Issue release date: 1993

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: http://www.karger.com/NPS

Abstract

The concept of rapid cycling is confusing in terms of its definition, clinical features, course of illness and the outcome. To complicate the matter further, rapid cycling has been reported to be drug resistant. Currently this condition has been reported to be secondary to lithium, tricyclic antidepressants and other agents such as cyproheptadine, a serotonin antagonist, piribedil, pro-pranolol and levodopa. The increase in rapid cycling has coincided with the rapid increase in cocaine use in the society even though such an association cannot prove a causal relationship. Clinical or subclinical hypothyroidism as well as hyperthyroidism have been implicated in rapid cycling. In addition to the lack of specific knowledge on the etiology, a number of heterogeneous disorders has been grouped under this entity. It is useful to attempt a classification to ascertain whether clinically distinguishable subgroups have a common or different pathophysiology and to tailor the treatment that is most desirable for each subgroup.

© 1993 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Biological Psychiatry

Published online: February 22, 2008
Issue release date: 1993

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: http://www.karger.com/NPS


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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