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Table of Contents
Vol. 25, No. 4, 2008
Issue release date: April 2008
Section title: Review Article
Dement Geriatr Cogn Disord 2008;25:293–300

Epilepsy and Dementia in the Elderly

Hommet C.a, b · Mondon K.b, c · Camus V.b, c · De Toffol B.d · Constans T.a
aGeriatric Internal Medicine and Regional Memory Centre, bInserm Unit 619, cRegional Memory Centre and dNeurology Unit, University Hospital, Tours University, Tours, France
email Corresponding Author

Caroline Hommet, MD, PhD

Geriatric Internal Medicine and Regional Memory Centre, University Hospital

Blvd Tonnellé

FR–37044 Tours Cedex (France)

Tel. +33 2 47 47 37 13, Fax +33 2 47 47 60 14, E-Mail hommet@med.univ-tours.fr

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Epilepsy is a frequent condition in the elderly; however, it remains a relatively understudied condition in older adults with dementia. The diagnosis of a seizure is particularly difficult and is most often based on questions to the caregiver. Epilepsy in dementia has significant consequences on the prognosis of the underlying dementia: it can result in a worsening of cognitive performance, particularly in language, as well as a reduction in autonomy, a greater risk of injury and a higher mortality rate. In this review, management strategies are recommended for the clinician. The presence of pre-existing Alzheimer’s disease does not exempt the clinician from ruling out other symptomatic causes of seizures. Anti-epileptic drugs (AED) should be started only after the diagnosis has been clearly established, when the risk of recurrence is high, and with monotherapy whenever possible. Although few data are available, the more recent AED offer significant advantages over the older medications in this context.

© 2008 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Review Article

Accepted: October 20, 2007
Published online: March 03, 2008
Issue release date: April 2008

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 1

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM

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