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Vol. 41, No. 1, 1986
Issue release date: 1986
Cytogenet Cell Genet 1986;41:38–41
(DOI:10.1159/000132193)
Original Article

Localization of the human haptoglobin genes distal to the fragile site at 16q22 using in situ hybridization

Simmers R.N. · Stupans I. · Sutherland G.R.
Cytogenet Genome Res Unit, Department of Histopathology, Adelaide Children’s Hospital, North Adelaide

Abstract

The distamycin A-sensitive fragile site fra(16)(q22) is a precisely localized chromosomal marker. When expressed at metaphase, it visibly separates the chromosome material on either side of the fragile site. Using a cDNA probe encoding both the α and β haptoglobin chains, the haptoglobin loci were found by in situ hybridization to be distal to fra(16)(q22).

 goto top of outline Author Contacts

Request reprints from: Ruth N. Simmers, Cytogenet Genome Res Unit, Department of Histopathology, Adelaide Children’s Hospital, North Adelaide, South Australia 5006 (Australia).


 goto top of outline Article Information

Received:: 25 March 1985
Published online: May 08, 2008
Number of Print Pages : 4


 goto top of outline Publication Details

Cytogenetic and Genome Research

Vol. 41, No. 1, Year 1986 (Cover Date: 1986)

Journal Editor: Schmid M. (Würzburg)
ISSN: 1424–8581 (Print), eISSN: 1424–859X (Online)

For additional information: http://www.karger.com/CGR


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