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Vol. 71, No. 1, 1995
Issue release date: 1995
Cytogenet Cell Genet 1995;71:44–46
Gene Mapping, Cloning, and Sequencing

Lysosomal chitobiase (CTB) and the G-protein γ5 subunit (GNG5) genes co-localize to human chromosome 1p22

Ahmad W.a · Li S.b · Chen H.b · Tuck-Muller C.M.b · Pittler S.J.a · Aronson Jr. N.N.a
Departments of aBiochemistry and Molecular Biology and bMedical Genetics, College of Medicine, University of South Alabama, Mobile AL (USA)


Previously isolated human placental cDNA clones represent a fusion of specific RNA sequences encoded by two genes: lysosomal chitobiase (CTB) and G-protein γ5 subunit (GNG5, Fisher and Aronson, 1992a, 1992b). Both genes have now been mapped to 1p by PCR analysis of somatic cell hybrids and further refined to 1p22 by fluorescence in situ hybridization (FISH) using a YAC clone that contains both the chitobiase and 75 genes.

 goto top of outline Author Contacts

Request reprints from Dr. Nathan N. Aronson Jr., Department of Biochemistry and Molecular Biology, College of Medicine, University of South Alabama, Mobile AL 36688-002 USA; telephone: 334-60-402; fax: 334-60-127.

 goto top of outline Article Information

Received: 24 October 1994
Published online: May 16, 2008
Number of Print Pages : 3

 goto top of outline Publication Details

Cytogenetic and Genome Research

Vol. 71, No. 1, Year 1995 (Cover Date: 1995)

Journal Editor: Schmid M. (Würzburg)
ISSN: 1424–8581 (Print), eISSN: 1424–859X (Online)

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