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Vol. 72, No. 2-3, 1996
Issue release date: 1996
Section title: Gene Mapping, Cloning, and Sequencing
Cytogenet Cell Genet 1996;72:179–182
(DOI:10.1159/000134181)

Mapping of the metalloproteinase gene matrilysin (MMP7) to human chromosome 11q21→q22

Knox J.D. · Boreham D.R. · Walker J.-A. · Morrison D.P. · Matrisian L.M. · Nagle R.B. · Bowden G.T.
aDepartment of Pathology, University of Arizona, Tucson AZ (USA); bAtomic Energy of Canada Ltd., Chalk River, Ontario (Canada); cDepartment of Cell Biology, Vanderbilt University, Nashville, TN; and dDepartment of Radiation Oncology, University of Arizona, Tucson AZ (USA)

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Article / Publication Details

First-Page Preview
Abstract of Gene Mapping, Cloning, and Sequencing

Accepted: 5/5/1995
Published online: 5/16/2008

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: http://www.karger.com/CGR

Abstract

The matrix metalloproteinase, matrilysin, is thought to play an important role in the early steps of tumor progression. We determined the chromosome location of the matrilysin gene (MMP7) by Southern and PCR analysis of two different panels of somatic cell hybrids and in situ hybridization of metaphase chromosomes. Matrilysin maps to the region, 11q21→q22, adding MMP7 to the cluster of matrix metalloproteinase genes that have already mapped to this region.


  

Author Contacts

Request reprints from Dr. J. David Knox, Department of Pathology, University of Arizona, 1501 N. Campbell Ave, Tucson AZ 85724 (USA); telephone: 602-626-6747; fax: 602-626-4480; e-mail: knoxj@as.uug.arizona.edu

  

Article Information

Received: 5 May 1995
Published online: May 16, 2008
Number of Print Pages : 4

  

Publication Details

Cytogenetic and Genome Research

Vol. 72, No. 2-3, Year 1996 (Cover Date: 1996)

Journal Editor: Schmid M. (Würzburg)
ISSN: 1424–8581 (Print), eISSN: 1424–859X (Online)

For additional information: http://www.karger.com/CGR


Article / Publication Details

First-Page Preview
Abstract of Gene Mapping, Cloning, and Sequencing

Accepted: 5/5/1995
Published online: 5/16/2008

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: http://www.karger.com/CGR


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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