Gene Mapping, Cloning, and Sequencing
Assignment of the human GATA4 gene to 8p23.1→p22 using fluorescence in situ hybridization analysisHuang W.-Y.a · Heng H.H.Q.a · Liew C.-C.a,b
Departments of aClinical Biochemistry and bMedicine, Laboratory for Molecular Cardiology, The Centre for Cardiovascular Research, The Toronto Hospital, University of Toronto, Toronto, Ont. M5G 1L5 (Canada)
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Using fluorescence in situ hybridization, the human GATA4 gene, a member of the zinc-finger protein family recognizing the consensus GATA motif, was mapped to 8p23.1→p22. This result, in conjunction with gene mapping data on other GATA-DNA binding proteins, suggests that genes encoding GATA-DNA binding proteins are dispersed throughout the genome, rather than clustered within a single locus.
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