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Vol. 72, No. 4, 1996
Issue release date: 1996
Cytogenet Cell Genet 1996;72:294–296
Gene Mapping, Cloning, and Sequencing

Assignment of the human α-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization

Wilton SD.a · Lim L.a · Dorosz S.D.a · Gunn H.C.a · Eyre H.J.b · Callen D.F.b · Laing N.G.a
aAustralian Neuromuscular Research Institute, QEII Medical Centre, Nedlands, Western Australia, andaCentre for Medical Genetics, Department of Cytogenetics and Molecular Genetics, Women’s and Children’s Hospital, Adelaide, South Australia (Australia)


Sequence-tagged sites (STSs) were developed for the human α-tropomyosin gene TPM4. One STS was used to amplify DNA from somatic cell hybrids to localize TPM4 to chromosome 19. The other, a product from a long-range PCR, was used directly as a probe to refine the localization of TPM4 to 19p13.1 by fluorescence in situ hybridization to metaphase chromosome spreads.

 goto top of outline Author Contacts

Request reprints from Dr. S.D. Wilton, Australian Neuromuscular Research Institute, 4th Floor “A” Block, QE II Medical Centre, Nedlands, Western Australia 6009 (Australia); telephone: 61-9-346-3967; fax: 61-9-346-3487.

 goto top of outline Article Information

Received: 22 May 1995
Published online: May 16, 2008
Number of Print Pages : 3

 goto top of outline Publication Details

Cytogenetic and Genome Research

Vol. 72, No. 4, Year 1996 (Cover Date: 1996)

Journal Editor: Schmid M. (Würzburg)
ISSN: 1424–8581 (Print), eISSN: 1424–859X (Online)

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