Journal Mobile Options
Table of Contents
Vol. 73, No. 1-2, 1996
Issue release date: 1996
Cytogenet Cell Genet 1996;73:130–133
Gene Mapping, Cloning, and Sequencing

Isolation and mapping of a human gene (RPD3L1) that is homologous to RPD3, a transcription factor in Saccharomyces cerevisiae

Furukawa Y.a,b · Kawakami T.a · Sudo K.a · Inazawa J.c · Matsumine A.d · Akiyama T.d · Nakamura Y.a
aLaboratory of Molecular Medicine, The Institute of Medical Science, The University of Tokyo; bFirst Department of Surgery, The University of Tokyo, Tokyo; cDepartment of Hygiene, Kyoto Prefectural University of Medicine, Kyoto; dDepartment of Oncogene Research, Research Institute for Microbial Diseases, Osaka University, Osaka (Japan)


We have isolated a novel human gene RPD3L1, that is highly homologous to a transcription factor in Saccharomyces cerevisiae, RPD3 (reduced potassium dependency 3), from a human fetal lung cDNA library. The cDNA clone, hRPD3, consists of 2,100 nucleotides that contain an open reading frame of 1446 nucleotides encoding 482 amino acids. It shares 62% identity in nucleotide sequence and 52% identity in amino acid sequence to RPD3. This gene is expressed at various levels in all tissues examined. Furthermore, we were able to map it to chromosome band 1p34.1 by FISH.

 goto top of outline Author Contacts

Request reprints from Yusuke Nakamura, M.D., Ph.D., Laboratory of Molecular Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108 (Japan); telephone: 81-3-5449-5372; fax: 81-3-5449-5433; e-mail:

 goto top of outline Article Information

Received: 5 July 1995
Published online: May 20, 2008
Number of Print Pages : 4

 goto top of outline Publication Details

Cytogenetic and Genome Research

Vol. 73, No. 1-2, Year 1996 (Cover Date: 1996)

Journal Editor: Schmid M. (Würzburg)
ISSN: 1424–8581 (Print), eISSN: 1424–859X (Online)

For additional information:

Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.