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Vol. 78, No. 1, 1997
Issue release date: 1997
Cytogenet Cell Genet 1997;78:31–35
(DOI:10.1159/000134621)
Gene Mapping, Cloning, and Sequencing

Molecular cloning and mapping of a human cDNA (PA2G4) that encodes a protein highly homologous to the mouse cell cycle protein P38-2G4

Lamartine J.a · Seri M.b · Cinti R.b · Heitzmann F.a · Creaven M.a,b · Radomski N.c · Jost E.c · Lenoir G.M.a · Romeo G.a,b · Sylla B.S.a
aInternational Agency for Research on Cancer, Lyon (France); bLaboratorio di Genetica Molecolare, Istituto G. Gaslini, Largo G. Genova Quarto (Italy); cJustus Liebig-Universität, Giessen (Germany)

Abstract

We have identified a novel human gene with strong homology to the mouse Pa2g4 cell cycle gene. This novel gene (called PA2G4) belongs to a gene family with members in several chromosome regions: 3q24-q25, 6q22, 9q21, 12q13, 18q12, 20p12 and Xq25. A composite cDNA of 1697 nucleotides was isolated. The sequence of this cDNA predicts a protein of 394 amino acids. The deduced amino acid sequence of this human protein shows very strong homology to the mouse protein p38–2G4. The cDNA analyzed probably corresponds to a functional copy found at 12q13.

 goto top of outline Author Contacts

Request reprints from Dr. Bakary S. Sylla, International Agency for Research on Cancer, 150 Cours A. Thomas, F 69372 Lyon Cedex 08 (France); telephone: (33) 4 72 73 84 85; fax: (33) 4 72 73 85 75; e-mail: sylla@iarc.fr


 goto top of outline Article Information

Received: 19 February 1997
Published online: May 20, 2008
Number of Print Pages : 5


 goto top of outline Publication Details

Cytogenetic and Genome Research

Vol. 78, No. 1, Year 1997 (Cover Date: 1997)

Journal Editor: Schmid M. (Würzburg)
ISSN: 1424–8581 (Print), eISSN: 1424–859X (Online)

For additional information: http://www.karger.com/CGR


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