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Table of Contents
Vol. 42, No. 4, 2008
Issue release date: August 2008
Section title: Original Paper
Caries Res 2008;42:275–281
(DOI:10.1159/000135673)

Fractional Urinary Fluoride Excretion of Young Female Adults during the Diurnal and Nocturnal Periods

Villa A.a · Anabalón M.a · Cabezas L.a · Rugg-Gunn A.b
aInstitute of Nutrition and Food Technology, INTA, University of Chile, Santiago, Chile; bUniversity of Newcastle upon Tyne, Newcastle upon Tyne, UK

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: August 02, 2007
Accepted: March 14, 2008
Published online: June 04, 2008
Issue release date: August 2008

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 2

ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)

For additional information: http://www.karger.com/CRE

Abstract

Objectives: This study aimed to confirm a previously obtained value for the fractional urinary fluoride excretion (FUFE) over a 24-hour period in adults and to assess whether there are significant differences between FUFE measured during the diurnal (7 a.m. and 6 p.m.) and the subsequent nocturnal (6 p.m. until 7 a.m. of the following day) periods. Methods: Urine was collected over 24 h from 60 healthy female volunteers residing in Santiago, Chile. The individuals’ fluoride intakes over the diurnal and nocturnal periods were calculated from their corresponding F ingestion, measured by dietary analysis. Separate urine collections during both periods were obtained from each volunteer. The fluoride concentrations were measured with a fluoride-ion-selective electrode either directly (urine, water and beverages) or after sample treatment with the microdiffusion technique (food). Results: The average 24-hour FUFE value was 0.69, with a 95% CI of 0.65–0.72, while the average FUFE for the diurnal period was 0.46 (95% CI: 0.42–0.50), and the corresponding result for the nocturnal period showed a significantly higher (paired t test, p < 0.0001) amount of 1.09 (95% CI: 0.97–1.22). Conclusions: A recently published result for the daily FUFE value (0.71) in adults was confirmed. The diurnal average FUFE value is significantly lower than the average nocturnal one. Accepting that approximately 10% of the fluoride intake is not absorbed, the daily fluoride retention can be preliminarily estimated as 20% of the ingested fluoride.

© 2008 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: August 02, 2007
Accepted: March 14, 2008
Published online: June 04, 2008
Issue release date: August 2008

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 2

ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)

For additional information: http://www.karger.com/CRE


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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