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Table of Contents
Vol. 96, No. 2, 1976
Issue release date: 1976
Section title: Paper
Acta Anatomica 1976;96:188–195
(DOI:10.1159/000144672)

Study in the changes of the proportions and numbers of the various glial cell types in the spinal cord of neonatal and young adult rats

Ling E.A.
Department of Anatomy, Faculty of Medicine, University of Singapore, Singapore, Singapore

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Article / Publication Details

First-Page Preview
Abstract of Paper

Received: July 17, 1975
Published online: July 09, 2008
Issue release date: 1976

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 1422-6405 (Print)
eISSN: 1422-6421 (Online)

For additional information: http://www.karger.com/CTO

Abstract

Glioblasts, astrocytes, microglia and the three classes of oligodendrocytes were enumerated in the grey and white matter of the spinal cord of rats of various ages. Both regions showed fairly similar results. Glioblasts, which made up the major glial population in the newborn rats, declined steadily with age and their number became negligible by 22 days post natum. They were absent in the young adult rats (aged 70 days). Contrary to this, the major glial types increased rapidly with age, the increase being most drastic in the oligodendrocy tic population. The growth continued through about 22 days after birth and became more or less stabilized thereafter. Of the three classes of oligodendrocytes, the light cells appeared to develop first, followed by the medium dense cells and subsequently the dark ones. While there was a gradual disappearance of the light and medium dense cells with age, there was an accumulation of the dark cells, so that they were predominant in the spinal cord of the young adult rats.

© 1976 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Paper

Received: July 17, 1975
Published online: July 09, 2008
Issue release date: 1976

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 1422-6405 (Print)
eISSN: 1422-6421 (Online)

For additional information: http://www.karger.com/CTO


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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