Journal Mobile Options
Table of Contents
Vol. 139, No. 1, 1990
Issue release date: 1990
Add to my selection Citation Download
Acta Anatomica 1990;139:31–44
(DOI:10.1159/000146975)
Paper

Smooth Muscle Cells, Interstitial Cells of Cajal and Myenteric Plexus Interrelationships in the Human Colon

Faussone-Pellegrini M.S.a · Pantalone D.b · Cortesini C.b
aDepartment of Human Anatomy and Histology, Section of Histology, bClinica Chirurgica 3, University of Florence, Italy Acta Anatomica 1990;139:31–44 (DOI:10.1159/000146975)

Abstract

The plane between longitudinal and circular muscle of human colon, as revealed on examination with light and electron microscopes, has no clear-cut border. Some groups of smooth muscle cells, obliquely oriented and with features similar to both circular and longitudinal ones – the connecting muscle bundles – run from one muscle layer to another. Other groups of smooth muscle cells, possessing their own specific ultrastructural features – the myenteric muscle sheaths - make up envelopes of variable thickness around some myenteric ganglia and nerve strands, partially or completely embedding them in one or other muscle layer. Non-neuronal, non-muscular cells (interstitial cells of Cajal, covering cells, fibroblast-like and macrophage-like cells) complicate the texture of the myenteric muscle sheaths, creating an intricate, interconnected cellular network inside them, widespread among nerve bundles and smooth muscle cells; however, only interstitial cells have cell-to-cell junctions also with the smooth muscle cells and nerve endings. These data document the existence in this colonic area of two different types of muscle cell arrangements, one of which, the myenteric muscle sheath, only contains putative pacemaker cells.

 goto top of outline Author Contacts

M.S. Faussone-Pellegrini, Department Human Anatomy and Histology, Section of Histology, Viale G. Pieraccini 6, I-50134 Firenze (Italy)


 goto top of outline Article Information

Received: September 15, 1989
Accepted: December 12, 1989
Published online: July 16, 2008
Number of Print Pages : 14


 goto top of outline Publication Details

Cells Tissues Organs (in vivo, in vitro)

Vol. 139, No. 1, Year 1990 (Cover Date: 1990)

Journal Editor: Denker H.-W. (Essen), English A.W. (Atlanta, Ga.)
ISSN: 1422–6405 (Print), eISSN: 1422–6421 (Online)

For additional information: http://www.karger.com/CTO


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.