98 antisera prepared against 25 simian adenoviruses and 31 adenovirus types from various nonprimate mammals and birds were tested for their ability to neutralize 35 human adenovirus prototypes. Antisera to these human adenovirus types were similarly tested against 25 simian adenovirus prototypes. Although very few reactions to the human adenoviruses were found in antisera to nonprimate viruses, cross-reactions among the simian and human adenoviruses were more frequent. The majority of these reactions, however, were of low titer and of questionable significance. Two chimpanzee adenovirus strains – Pan 9 and SAV 21 (C 1) – were found with an immunological relationship to human adenoviruses: Pan 9 strain showed a two-way cross relationship to human adenovirus 4, and SAV 21 (C 1) was neutralized by antisera prepared against human adenoviruses 14 and 16.
Address inquiries to: Dr. R. Wigand, Abteilung für Virologie, Institut für Hygiene und Mikrobiologie, Universitätskliniken Haus 47, D-6650 Homburg/Saar (FRG)
Received: July 23, 1980
Revised: January 6, 1981
Published online: July 24, 2008
Number of Print Pages : 9
Intervirology (International Journal of Basic and Medical Virology)
Vol. 15, No. 1, Year 1981 (Cover Date: 1981)
Journal Editor: Liebert U.G. (Leipzig)
ISSN: 0300–5526 (Print), eISSN: 1423–0100 (Online)
For additional information: http://www.karger.com/INT
Copyright / Drug Dosage
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