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Vol. 8, No. 6, 1971
Issue release date: 1971
Angiologica 1971;8:285–296
(DOI:10.1159/000157902)
Paper

Responsiveness of the Terminal Vascular Bed in Fast and Slow Skeletal Muscles to α-Adrenergic Stimulation

Gray S.D.
Department of Physiology, Mt. Sinai School of Medicine, City University of New York, New York, NY. Angiologica 1971;8:285–296 (DOI:10.1159/000157902)

Abstract

In the light of known differences in bio-chemical, histological, and biophysical characteristics of fast and slow muscle, it was thought feasible to investigate possible differences in vascular properties. The present study has shown that vascular reactivity to α-adrenergic stimulation by both topical application of catecholamines (epinephrine and norepinephrine) and reflex activation of sympathetic nerves, is graded in both fast and slow muscles from precapillary sphincters which are the most sensitive, to small and then larger arterioles. In addition, the vessels of fast muscle are more sensitive to stimulation by those agents than are the vessels of slow muscle. The vascular bed in fast muscle is characterized by vasomotion (intermittency of flow rate and pattern) and many momentarily inactive capillaries (no moving red cells) in the resting state, whereas the flow in slow muscle capillaries is much more steady and uniform.

 goto top of outline Author Contacts

Author’s address: Dr. Sarah D. Gray, Department of Physiology, Mt. Sinai School of Medicine, City University of New York, 10 E. 102nd Street, New York, NY 10029 (USA)


 goto top of outline Article Information

Published online: September 18, 2008
Number of Print Pages : 12


 goto top of outline Publication Details

Journal of Vascular Research (Incorporating 'International Journal of Microcirculation')

Vol. 8, No. 6, Year 1971 (Cover Date: 1971)

Journal Editor: Pohl U. (Munich), Meininger G.A. (Columbia, Mo.)
ISSN: 1018–1172 (Print), eISSN: 1423–0135 (Online)

For additional information: http://www.karger.com/JVR


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