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Table of Contents
Vol. 42, No. 6, 2008
Issue release date: November 2008
Section title: Short Communication
Free Access
Caries Res 2008;42:444–448

Streptococcus mutans and Streptococcus sanguinis Colonization Correlated with Caries Experience in Children

Ge Y.a · Caufield P.W.b · Fisch G.S.c · Li Y.a
Departments of aBasic Science and Craniofacial Biology, bCariology and Comprehensive Care and cEpidemiology and Health Promotion, New York University College of Dentistry, New York, N.Y., USA
email Corresponding Author

Dr. Yihong Li

New York University College of Dentistry

345 E. 24th Street

New York, NY 10010-4086 (USA)

Tel. +1 212 998 9607, Fax +1 212 995 4087, E-Mail yihong.li@nyu.edu

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The aim of this study was to examine the colonization of Streptococcus mutans and Streptococcus sanguinis in the oral cavity and the association with severe early childhood caries (S-ECC). Saliva and plaque samples were collected from 14 S-ECC children and 8 caries-free (CF) children. All S-ECC children were S. mutans positive; 100% of CF children and 93% of S-ECC children were S. sanguinis positive. The children’s caries severity was positively correlated with levels of S. mutans (p < 0.001), total oral streptococci (p < 0.01), total cultivable oral bacteria (p < 0.05), and children’s age (p < 0.05). Logistic regression analysis showed that the interaction of S. sanguinis with S. mutans was a significant factor associated with the caries status in children, suggesting that the relative levels of these two microorganisms in the oral cavity play an important role in caries development.

© 2008 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Short Communication

Received: November 20, 2007
Accepted: August 06, 2008
Published online: October 03, 2008
Issue release date: November 2008

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 3

ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)

For additional information: http://www.karger.com/CRE

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