Objective: To determine from a large cohort of women eligible for screening mammography, the number who would meet criteria for genetic testing for hereditary nonpolyposis colorectal cancer (HNPCC). Methods: Detailed personal and family cancer histories, obtained from 6,682 women aged 50–80 years randomly selected from communities in Washington State, were matched to the Amsterdam criteria, Bethesda guidelines, and Japanese criteria for HNPCC. Results: One (0.015%) respondent met the Amsterdam criteria, 2 (0.035%) met the Japanese criteria and 5 (0.075%) met the Bethesda guidelines. Conclusion: Using the time of presentation for initial mammography as an opportunity to screen for HNPCC would detect very few families at high risk for this condition.
© 2000 S. Karger AG, Basel
Scott D. Ramsey
Center for Cost and Outcomes Research, University of Washington
146 North Canal Street, Suite 300
Seattle, WA 98103 (USA)
Tel. +1 206 543 4943, Fax +1 206 543 5318, E-Mail email@example.com
Number of Print Pages : 6
Number of Figures : 0, Number of Tables : 5, Number of References : 29
Vol. 2, No. 4, Year 1999 (Cover Date: Released June 2000)
Journal Editor: L.P. ten Kate, Amsterdam
ISSN: 1422–2795 (print), 1422–2833 (Online)
For additional information: http://www.karger.com/journals/cmg
Article / Publication Details
Published online: 6/13/2000
Issue release date: June 2000
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 5
ISSN: 1662-4246 (Print)
eISSN: 1662-8063 (Online)
For additional information: http://www.karger.com/PHG
Copyright / Drug Dosage
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.