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Vol. 78, No. 1, 2009
Issue release date: December 2008
Section title: Special Article
Psychother Psychosom 2009;78:6–15
(DOI:10.1159/000162296)

Psychological Intervention for Premenstrual Syndrome: A Meta-Analysis of Randomized Controlled Trials

Busse J.W. · Montori V.M. · Krasnik C. · Patelis-Siotis I. · Guyatt G.H. ·
aDepartment of Clinical Epidemiology and Biostatistics, bDepartment of Medical Science, Psychiatry and Behavioural Neuroscience, and cDepartment of Psychiatry, McMaster University, Hamilton, Ont., Canada; dKnowledge and Encounter Research Unit, Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn., USA

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Article / Publication Details

First-Page Preview
Abstract of Special Article

Published online: 10/14/2008

Number of Print Pages: 10
Number of Figures: 3
Number of Tables: 2

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS

Abstract

Background: We conducted a systematic review and meta-analysis to determine the efficacy of psychological interventions for premenstrual syndrome. Methods: We systematically searched and selected studies that enrolled women with premenstrual syndrome in which investigators randomly assigned them to a psychological intervention or to a control intervention. Trials were included irrespective of their outcomes and, when possible, we conducted meta-analyses. Results: Nine randomized trials, of which 5 tested cognitive behavioural therapy, contributed data to the meta-analyses. Low quality evidence (design and implementation weaknesses of the studies, possible reporting bias) suggests that cognitive behavioural therapy significantly reduces both anxiety (effect size [ES] = –0.58; 95% confidence interval [CI] = –1.15 to –0.01; number needed to treat [NNT] = 5), and depression (ES = –0.55; 95% CI = –1.05 to –0.05; NNT = 5), and also suggests a possible beneficial effect on behavioural changes (ES = –0.70; 95% CI = –1.29 to –0.10; NNT = 4) and interference of symptoms on daily living (ES = –0.78; 95% CI = –1.53 to –0.03; NNT = 4). Results provide much more limited support for monitoring as a form of therapy and suggest the ineffectiveness of education. Conclusions: Low quality evidence from randomized trials suggests that cognitive behavioural therapy may have important beneficial effects in managing symptoms associated with premenstrual syndrome.


  

Author Contacts

Dr. Jason W. Busse
CLARITY Research Group, Department of Surgery, McMaster University
293 Wellington St. North, Suite 110
Hamilton, ON L8L 8E7 (Canada)
Tel. +1 905 527 4322, ext. 44490, Fax +1 905 523 8781, E-Mail j.busse@utoronto.ca

  

Article Information

Published online: October 14, 2008
Number of Print Pages : 10
Number of Figures : 3, Number of Tables : 2, Number of References : 54

  

Publication Details

Psychotherapy and Psychosomatics

Vol. 78, No. 1, Year 2009 (Cover Date: December 2008)

Journal Editor: Fava G.A. (Bologna)
ISSN: 0033–3190 (Print), eISSN: 1423–0348 (Online)

For additional information: http://www.karger.com/PPS


Article / Publication Details

First-Page Preview
Abstract of Special Article

Published online: 10/14/2008

Number of Print Pages: 10
Number of Figures: 3
Number of Tables: 2

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS


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