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Vol. 95, No. 3, 2009
Issue release date: March 2009
Section title: Original Paper
Neonatology 2009;95:217–223
(DOI:10.1159/000165980)

Continuous Glucose Monitoring in Infants of Very Low Birth Weight

Iglesias Platas I.a · Thió Lluch M.a · Pociello Almiñana N.b · Morillo Palomo A.a · Iriondo Sanz M.a · Krauel Vidal X.a
aNeonatal Unit, Hospital Sant Joan de Déu, Fundació Sant Joan de Déu, Barcelona University, Barcelona, and bDivision of Pediatrics, Hospital Arnau de Vilanova, Lleida, Spain

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 1/22/2008
Accepted: 4/28/2008
Published online: 10/30/2008
Issue release date: March 2009

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 4

ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)

For additional information: http://www.karger.com/NEO

Abstract

Objectives: To evaluate the feasibility and efficacy of a continuous glucose monitoring system (CGMS) in a population of infants of very low birth weight (VLBW). Study Design: Infants weighing ≤1,500 g and of ≤32 weeks of gestation were recruited within 24 h of delivery. A subcutaneous sensor connected to a CGMS was inserted and maintained for 7 days or until dysfunction. Therapeutic management followed the usual standard protocols. Results: 38 patients (21 male) were included over 17 months. Their mean gestational age was 27.5 ± 2.0 weeks and their mean birth weight was 958.3 ± 205.5 g. Their perinatal histories and complications during admission were unremarkable for extremely premature babies. Continuous monitoring lasted an average of 7.84 ± 1.99 days per patient. Hyperglycaemia was detected in 22 (57.90%) patients and it lasted a mean of 20.33 ± 30.13 h, while 14 (36.8%) presented with hypoglycaemia for a mean of 2.45 ± 2.3 h. Conclusions: The CGMS gave a safe and useful estimate of glucose levels in VLBW infants, revealing abnormal glucose levels at a much higher rate than expected by usual sampling. However, it was not able to provide real-time glucose concentration data. CGMS may be very useful in providing information on the role of hyper- and hypoglycaemia on short- and long-term outcomes in VLBW infants.

© 2008 S. Karger AG, Basel


  

Author Contacts

Isabel Iglesias Platas, MD, MSc
Neonatal Unit, Hospital Sant Joan de Déu
Passeig Sant Joan de Déu s/n, Esplugues de Llobregat
ES–08950 Barcelona (Spain)
Tel. +34 9 3240 8000 (ext. 2402), Fax +34 9 3203 3959, E-Mail iiglesias@hsjdbcn.org

  

Article Information

Received: January 22, 2008
Accepted after revision: April 28, 2008
Published online: October 30, 2008
Number of Print Pages : 7
Number of Figures : 2, Number of Tables : 4, Number of References : 32

  

Publication Details

Neonatology (Fetal and Neonatal Research)

Vol. 95, No. 3, Year 2009 (Cover Date: March 2009)

Journal Editor: Halliday H.L. (Belfast), Speer C.P. (Würzburg)
ISSN: 1661–7800 (Print), eISSN: 1661–7819 (Online)

For additional information: http://www.karger.com/NEO


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 1/22/2008
Accepted: 4/28/2008
Published online: 10/30/2008
Issue release date: March 2009

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 4

ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)

For additional information: http://www.karger.com/NEO


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