Epidemiology, Risk Factors and Treatments for Antibiotic-Associated DiarrheaMcFarland L.V.
Department of Medicinal Chemistry, School of Pharmacy, University of Washington and Biocodex, Inc., Seattle Wash., USA
Antibiotic-associated diarrhea (AAD) is a common complication of antibiotics and recent findings on the epidemiology, etiologies and treatment strategies are reviewed. Rates of AAD vary from 5 to 39% depending upon the specific type of antibiotic. The severity of AAD may include uncomplicated diarrhea, colitis or pseudomembranous colitis. The pathogenesis of AAD may be mediated through the disruption of the normal flora and overgrowth of pathogens or through metabolic imbalances. The impact of AAD is reflected by increased hospital stays, higher medical costs and increased rates of comorbidity. The key to decreasing these consequences is prompt diagnosis followed by effective treatment and institution of control measures.
Lynne V. McFarland, PhD
1910 Fairview Aavenue East, Suite 208
Seattle, WA 98102 (USA)
Tel. +1 206 322 5663, Fax +1 206 323 2968
Number of Print Pages : 16
Number of Figures : 0, Number of Tables : 5, Number of References : 155
Digestive Diseases (Current Concepts in Research and Practice)
Formerly ‘Survey of Digestive Diseases’; Founded in 1983 by T.S.N. Chen and R.K. Zetterman
Vol. 16, No. 5, Year 1998 (Cover Date: September-October 1998< (Released January 1999))
Journal Editor: S.R. Achem, Jacksonville, Fla.
ISSN: 0257–2753 (print), 1421–9875 (Online)
For additional information: http://www.karger.com/journals/ddi