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Vol. 17, No. 2, 1999
Issue release date: 1999
Section title: Review Article
Dig Dis 1999;17:100–106
(DOI:10.1159/000016911)

Clinical Features of Celiac Disease Today

Collin P. · Kaukinen K. · Mäki M.
Departments of Medicine and Paediatrics, Tampere University Hospital, Medical School and Institute of Medical Technology, University of Tampere, Finland

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Article / Publication Details

First-Page Preview
Abstract of Review Article

Published online: 9/27/1999

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 2

ISSN: 0257-2753 (Print)
eISSN: 1421-9875 (Online)

For additional information: http://www.karger.com/DDI

Abstract

The clinical spectrum of celiac disease has widened over the past decades. The condition is no longer a severe malabsorption syndrome. Instead, a typical celiac disease patient today has merely mild abdominal symptoms. Malabsorption can be subclinical or absent, and there is usually only moderate, if any, loss of weight. Simultaneously, the current prevalence has increased from 1:1,000 to 1:300 inhabitants, or even higher. Clinically silent celiac disease cases are being detected in increasing numbers since the introduction and widespread use of serologic screening tests. Symptoms of celiac disease can appear outside the intestine, a typical example being dermatitis herpetiformis. Gluten intolerance is no longer limited to overt villous atrophy. Inflammation without villous damage may be observed in genetically susceptible individuals. The term latent celiac disease is applied in situations where the patient has normal villous architecture while on a gluten-containing diet, but later develops small bowel villous atrophy compatible with celiac disease.


  

Author Contacts

Pekka Collin
Medical School, University of Tampere
PO Box 607
FIN–33101 Tampere (Finland)
Tel. +358 3 247 5111, Fax +358 3 215 7746, E‐Mail pekka.collin@uta.fi

  

Article Information

Number of Print Pages : 7
Number of Figures : 0, Number of Tables : 2, Number of References : 90

  

Publication Details

Digestive Diseases (State-of-the-Art Clinical Reviews)
Formerly ‘Survey of Digestive Diseases’; Founded in 1983 by T.S.N. Chen and R.K. Zetterman

Vol. 17, No. 2, Year 1999 (Cover Date: 1999)

Journal Editor: S.R. Achem, Jacksonville, Fla.
ISSN: 0257–2753 (print), 1421–9875 (Online)

For additional information: http://www.karger.com/journals/ddi


Article / Publication Details

First-Page Preview
Abstract of Review Article

Published online: 9/27/1999

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 2

ISSN: 0257-2753 (Print)
eISSN: 1421-9875 (Online)

For additional information: http://www.karger.com/DDI


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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