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Vol. 12, No. 5, 1994
Issue release date: 1994
Dig Dis 1994;12:276–289

Alcohol and the Risk of Cancers of the Stomach and Colon-Rectum

Franceschi S.a · La Vecchia C.b
aEpidemiology Unit, Aviano Cancer Center, Aviano; bIstituto di Biometria e Statistica Medica, Università di Milano, and Istituto di Ricerche Farmacologiche ‘Mario Negri’, Milan, Italy


Alcohol drinking is strongly related to cancer of the upper digestive tract, but the pattern of risk with alcohol drinking is clearly different for cancer of the stomach and colon-rectum. All twelve cohort studies and three-quarters of 40 case-control investigations on the topic weigh against the possibility of a substantial effect of alcohol consumption on the risk of stomach cancer. Evidence is still insufficient to establish whether cancer of the cardiac region of the stomach is related to alcohol intake to any different extent than the rest of the stomach. With reference to colorectal cancer, different types of epidemiological studies are consistent in suggesting some direct relations with alcohol drinking. The association, however, is moderate, and an elevated risk of a factor 2 – or even of a factor 1.5 – for both cancers of the colon and rectum can now be excluded even for the highest levels of alcohol consumption.

 goto top of outline Author Contacts

Silvia Franceschi, Epidemiology Unit, Aviano Cancer Center, Via Pedemontana Occ., I-33081 Aviano (PN) (Italy)

 goto top of outline Article Information

Number of Print Pages : 14

 goto top of outline Publication Details

Digestive Diseases (Clinical Reviews)

Vol. 12, No. 5, Year 1994 (Cover Date: 1994)

Journal Editor: Malfertheiner P. (Magdeburg)
ISSN: 0257–2753 (Print), eISSN: 1421–9875 (Online)

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