Fasting during Ramadan Induces a Marked Increase in High-Density Lipoprotein Cholesterol and Decrease in Low-Density Lipoprotein CholesterolAdlouni A. · Ghalim N. · Benslimane A. · Lecerf J.M. · Saïle R.
aLaboratoire de recherches sur les lipoprotéines, Département de Biologie, Faculté des Sciences Ben M’sik, and bLaboratoire des Lipoprotéines, Institut Pasteur du Maroc, Casablanca, Morocco; cService de Nutrition, Institut Pasteur de Lille, France
We demonstrated for the first time in a Moroccan population that fasting during Ramadan, the ninth lunar month of the Muslims’ year, affected lipid and lipoprotein metabolism in a group of 32 healthy adult male volunteers. This investigation was conducted to study the changes in serum total cholesterol, triglycerides, cholesterol in high-density lipoprotein (HDL) and low-density lipoprotein (LDL), glucose, and body weight during Ramadan. The results showed a significant decrease (7.9%, p < 0.001) in serum total cholesterol concentration during Ramadan as compared with the prefasting period. Also, we obtained a significant decrease of serum triglyceride concentration (30%, p < 0.001) during Ramadan fasting as compared to the period before Ramadan. The reduction of both serum triglycerides and total cholesterol was maintained 1 month after Ramadan. By the end of Ramadan, serum HDL cholesterol had markedly increased (14.3%, p < 0.001) and remained elevated 1 month after Ramadan in contrast to LDL cholesterol which showed a significant decrease (11.7%, p < 0.001) also maintained 1 month after Ramadan. Mean body weight declined by 2.6% (p < 0.01) on day 29 of Ramadan, whereas during Ramadan, the diet pattern used by our subjects showed an increase of total energy intake due to carbohydrates (+1.4% of total energy), proteins (+0.4% of total energy) but not fat (-0.7% of total energy) compared to a usual diet used throughout the rest of the year. Moreover, the fat diet is high in monounsaturated (p < 0.05) and polyunsaturated fatty acid in contrast to saturated fatty acid which significantly (p < 0.05) decreased during Ramadan. These findings suggest that feeding behavior that occurs during Ramadan beneficially affects plasma lipids and lipoproteins.
Ahmed Adlouni, Laboratoire de recherches sur les lipoprotéines, Département de Biologie, Faculté des Sciences Ben M’sik, BP 7955, Sidi Othman, Casablanca (Morocco), Tel. (2) 70 46 72, fax (2) 70 46 75
Received: December 13, 1996
Accepted: May 13, 1997
Published online: November 20, 2008
Number of Print Pages : 8
Annals of Nutrition and Metabolism (Journal of Nutrition, Metabolic Diseases and Dietetics)
Vol. 41, No. 4, Year 1997 (Cover Date: 1997)
Journal Editor: Elmadfa I. (Vienna)
ISSN: 0250–6807 (Print), eISSN: 1421–9697 (Online)
For additional information: http://www.karger.com/ANM