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Table of Contents
Vol. 22, No. 2, 2009
Issue release date: February 2009
Section title: Paper
Skin Pharmacol Physiol 2009;22:55–62
(DOI:10.1159/000178864)

Stem Cells and Tissue-Engineered Skin

Charruyer A. · Ghadially R.
Department of Dermatology, University of California and Veterans Affairs Medical Center, San Francisco, Calif., USA

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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: 2/4/2009

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-5527 (Print)
eISSN: 1660-5535 (Online)

For additional information: http://www.karger.com/SPP

Abstract

Advances in tissue engineering of skin are needed for clinical applications (as in wound healing and gene therapy) for cutaneous and systemic diseases. In this paper we review the use of epidermal stem cells as a source of cells to improve tissue-engineered skin. We discuss the importance and limitations of epidermal stem cell isolation using biomarkers, in quest of a pure stem cell preparation, as well as the culture conditions necessary to maintain this purity as required for a qualitatively superior and long-lasting engineered skin. Finally, we review the advantages of using additional multipotent stem cell sources to functionally and cosmetically optimize the engineered tissue.


  

Author Contacts

Prof. Ruby Ghadially, MD
Dermatology Research, University of California, Department of Dermatology
Veteran’s Affairs Medical Center
4150 Clement Street MC190, San Francisco, CA 94121 (USA)
Tel. +1 415 221 4810, ext. 3373, Fax +1 415 750 6959, E-Mail ghadiallyr@derm.ucsf.edu

  

Article Information

Published online: February 4, 2009
Number of Print Pages : 8
Number of Figures : 0, Number of Tables : 0, Number of References : 74

  

Publication Details

Skin Pharmacology and Physiology (Journal of Pharmacological and Biophysical Research)

Vol. 22, No. 2, Year 2009 (Cover Date: February 2009)

Journal Editor: Lademann J. (Berlin)
ISSN: 1660-5527 (Print), eISSN: 1660-5535 (Online)

For additional information: http://www.karger.com/SPP


Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: 2/4/2009

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-5527 (Print)
eISSN: 1660-5535 (Online)

For additional information: http://www.karger.com/SPP


Copyright / Drug Dosage

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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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