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Table of Contents
Vol. 198, No. 2, 1999
Issue release date: 1999
Section title: Report
Dermatology 1999;198:212–217
(DOI:10.1159/000018116)

Fractal Quantification of the Microvasculature Heterogeneity in Cutaneous Melanoma

Heymans O.a · Blacher S.b · Brouers F.b · Piérard G.E.c
Departments of aPlastic Surgery, bChemical Engineering and cDermatopathology, University of Liège, Belgium

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Article / Publication Details

First-Page Preview
Abstract of Report

Published online: April 26, 1999
Issue release date: 1999

Number of Print Pages: 6
Number of Figures: 4
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Background: Recent advances in angiogenesis research have led to the introduction of new prognosis factors. Although the vessel count is effective in breast cancer, the prognosis of primary cutaneous melanoma (PCM) does not seems to be directly influenced by this parameter. However, the microscopic examination of PCM suggests variability in the repartition of the microvasculature. Objective and Method: To explore the possibility of extracting information about the vessel distribution by performing a textural analysis on the grey level of histological sections by means of fractal characterization by both Fourier spectrum and multifractal analysis. Results: Three different patterns of vasculature were identified according to the vessel density and distribution. Conclusion: It is possible to differentiate and quantify clearly the differences in the microvessel profile organization using the fractal and multifractal methods.


Article / Publication Details

First-Page Preview
Abstract of Report

Published online: April 26, 1999
Issue release date: 1999

Number of Print Pages: 6
Number of Figures: 4
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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