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Vol. 199, No. 1, 1999
Issue release date: 1999
Section title: Clinical and Laboratory Investigations
Dermatology 1999;199:8–14
(DOI:10.1159/000018196)

Mycosis fungoides in Patients under 20 Years of Age: Report of 7 Cases, Review of the Literature and Study of the Clinical Course

Quaglino P. · Zaccagna A. · Verrone A. · Dardano F. · Bernengo M.G.
Section of Dermatology, Department of Medical and Surgical Specialties, University of Turin, Italy

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Article / Publication Details

First-Page Preview
Abstract of Clinical and Laboratory Investigations

Published online: 8/6/1999

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 3

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Background: Mycosis fungoides (MF) is rare in young patients. Its clinical behavior is still uncertain, as some reports have suggested that it has a more aggressive course than does the adult-onset type. Aim: To ascertain if early-onset MF represents a heterogeneous group of cutaneous T cell lymphomas. Materials and Methods: Clinical, immunohistopathological and follow-up data of early-onset (<20 years of age) MF cases reported in the literature (n = 42) plus 7 described herein were compared with those of a cohort of adult-onset MF patients (n = 252) diagnosed at our institution since 1975. Results: The majority of the 49 early-onset MF patients had patch-plaque stage disease at diagnosis. Ten had hypopigmented lesions. The predominant phenotype was CD3+ CD4+CD7–CD8–. Seven patients had a stage progression, 6 with extracutaneous involvement. Five- and 10-year survival rates were 93 and 74%, respectively. Conclusions: No statistically significant differences were found in the disease course between early- and adult-onset MF.


  

Author Contacts

Prof. Maria Grazia Bernengo
Department of Medical and Surgical Specialties, Section of Dermatology
University of Turin, Via Cherasco 23
I–10126 Turin (Italy)
Tel. +39 11 633 58 16, Fax +39 11 67 40 34

  

Article Information

Received: Received: July 20, 1998
Accepted: February 19, 1999
Number of Print Pages : 7
Number of Figures : 2, Number of Tables : 3, Number of References : 41

  

Publication Details

Dermatology (International Journal for Clinical and Investigative Dermatology)
Founded as ‘Dermatologische Zeitschrift’ by Oskar Lassar (1893–1907); Continued by Erich Hoffmann (1908–1938), continued as ‘Dermatologica’ (1939–1991), by Wilhelm Lutz (1939–1958), Rudolf Schuppli (1959–1985)
Official Organ of the Swiss Society for Dermatology and Venereology; Official Organ of the Belgian Royal Society for Dermatology and Venereology

Vol. 199, No. 1, Year 1999 (Cover Date: 1999)

Journal Editor: J.-H. Saurat, Geneva.
ISSN: 1018–8665 (print), 1421–9832 (Online)

For additional information: http://www.karger.com/journals/drm


Article / Publication Details

First-Page Preview
Abstract of Clinical and Laboratory Investigations

Published online: 8/6/1999

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 3

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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