Between March 1964 and March 1980, 36 (34 dialysis, 2 transplant) of 327 patients accepted for the maintenance dialysis/transplantation programme at Charing Cross Hospital were submitted to parathyroidectomy. There were four main indications: persistent hypercalcaemia, progressive phalangeal erosions, aseptic necrosis of the femoral head and height loss with abnormal bone biopsy despite normal hand radiographs. At parathyroidectomy, 4 glands were removed in 1 patient, 3 ½ glands in 24, 3 glands in 7, 2 glands in 3 and a single large gland in 1 patient. The operation was followed by improvement in 28 patients, no change in 5, and progression of hyperparathyroidism in 3. 2 of the 28 patients who improved later relapsed and were treated with 1,25-(OH)2
. 4 patients were submitted to a further parathyroidectomy and improved considerably. We would conclude that, although parathyroidectomy is an effective and safe procedure, it is to be hoped that careful monitoring of bone state and early administration of 1,25-(OH)2
may reduce the need for parathyroidectomy.
Prof. H. E. de Wardener, Department of Medicine, Charing Cross Hospital, Fulham Palace Road, London W6 8RF (England)
Accepted: May 18, 1981
Published online: December 03, 2008
Number of Print Pages : 6
Vol. 30, No. 2, Year 1982 (Cover Date: 1982)
Journal Editor: Fine L.G. (Los Angeles, Calif.)
ISSN: 0028–2766 (Print), eISSN: 1423–0186 (Online)
For additional information: http://www.karger.com/NEF
Copyright / Drug Dosage
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