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Report

Comparative Anti-Dandruff Efficacy between a Tar and a Non-Tar Shampoo

Piérard-Franchimont C.a · Piérard G.E.a · Vroome V.b · Lin G.C.c · Appa Y.c

Author affiliations

aDepartment of Dermatopathology, University of Liège, and bJohnson & Johnson Consumer, Brussels, Belgium; cNeutrogena Skin Care Institute, Los Angeles, Calif., USA

Related Articles for ""

Dermatology 2000;200:181–184

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Article / Publication Details

First-Page Preview
Abstract of Report

Published online: April 14, 2000
Issue release date: 2000

Number of Print Pages: 4
Number of Figures: 3
Number of Tables: 2

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

A randomized double-blind clinical study was conducted on two groups of 30 volunteers using either a non-tar shampoo (2% salicylic acid, 0.75% piroctone olamine and 0.5% elubiol) or a 0.5% coal tar shampoo. Subjects were diagnosed as having moderate to marked dandruff. The study consisted of a 3-week washout, followed by a 4-week treatment and a 4-week posttreatment regression phase. The clinical evaluations and subject self-assessments showed that the non-tar shampoo was as effective as the tar shampoo. Both received high approval ratings (≥70%). Biometrological methods proved to be more sensitive than clinical evaluations to assess the efficacy of the shampoos. The non-tar shampoo yielded a significantly better reduction of Malassezia spp. counts (p < 0.02) during the treatment phase and reduced the spontaneous increase in squamometry values (p < 0.01) during the posttreatment phase. It is concluded that a formulation associating salicylic acid, piroctone olamine and elubiol exhibited increased beneficial effects compared to the coal tar shampoo.

© 2000 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Report

Published online: April 14, 2000
Issue release date: 2000

Number of Print Pages: 4
Number of Figures: 3
Number of Tables: 2

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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