Sacrococcygeal Teratomas: Prenatal Surveillance, Growth and Pregnancy OutcomeWilson R.D. · Hedrick H. · Flake A.W. · Johnson M.P. · Bebbington M.W. · Mann S. · Rychik J. · Liechty K. · Adzick N.S.
Fetal Heart Program, The Center for Fetal Diagnosis and Treatment, The Children’s Hospital of Philadelphia, and Departments of Surgery, Obstetrics/Gynecology, and Pediatrics, University of Pennsylvania, School of Medicine, Philadelphia, Pa., USA
Objective: Prenatal surveillance and growth characteristics are evaluated in a cohort of fetuses with sacrococcygeal teratomas (SCT) as part of risk assessment. Methods: Retrospective review of 23 fetuses with SCT: prenatal diagnosis, surveillance, delivery, and early postnatal outcome are reported. Results: Cardiac output failure physiology requires serial evaluation. The size of the SCT determines obstetrical risks and mode of delivery. An SCT growth rate approaching >150 cm3 per week may be associated with increased perinatal mortality risks. Maternal morbidity is related mainly to polyhydramnios and preterm labor. Conclusions: Perinatal mortality is approximately 43%. Maternal-fetal surgery for fetal physiologic deterioration is not frequent, but serial surveillance is required to minimize fetal morbidity/mortality and maternal morbidity. Rapid SCT growth rates may be associated with increased risk of perinatal mortality.
© 2008 S. Karger AG, Basel
Received: December 4, 2007
Accepted after revision: January 21, 2008
Published online: December 20, 2008
Number of Print Pages : 6
Number of Figures : 0, Number of Tables : 6, Number of References : 18
Fetal Diagnosis and Therapy (Clinical Advances and Basic Research)
Vol. 25, No. 1, Year 2009 (Cover Date: August 2009)
Journal Editor: Holzgreve W. (Freiburg), Evans M.I. (New York, N.Y.), Uzan S. (Paris), Michejda M. (Washington, D.C.), Pringle K.C. (Wellington)
ISSN: 1015-3837 (Print), eISSN: 1421-9964 (Online)
For additional information: http://www.karger.com/FDT