Journal Mobile Options
Table of Contents
Vol. 2, No. 3, 2008
Issue release date: January 2009
Section title: Original Paper
Curr Urol 2008;2:122–129
(DOI:10.1159/000189652)

Factor Analysis of the Expanded Prostate Cancer Index Composite in a Patient Group after Primary (External Beam Radiotherapy and Permanent Iodine-125 Brachytherapy) and Postoperative Radiotherapy for Prostate Cancer

Volz-Sidiropoulou E.a · Pinkawa M.b · Fischedick K.b · Jakse G.c · Gauggel S.a · Eble M.J.b
Department of aMedical Psychology and Medical Sociology, bRadiation Oncology and cUrology, RWTH Aachen University, Aachen, Germany

Do you have an account?

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger (new!)
  • Unrestricted printing, no saving restrictions for personal use
  • Reduced rates with a PPV account
read more

Direct: USD 38.00
Account: USD 26.50

Select

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply

Rental: USD 8.50
Cloud: USD 20.00

Select

Subscribe

  • Access to all articles of the subscribed year(s) guaranteed for 5 years
  • Unlimited re-access via Subscriber Login or MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

Subcription rates


Select


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 9/5/2008
Accepted: 10/31/2008
Published online: 1/7/2009
Issue release date: January 2009

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 1661-7649 (Print)
eISSN: 1661-7657 (Online)

For additional information: http://www.karger.com/CUR

Abstract

Background: The Expanded Prostate Cancer Index Composite questionnaire is widely used as a comprehensive assessment of health-related quality of life issues in prostate cancer management, distinguishing urinary, bowel, sexual, hormonal domains. The primary purpose of this study was to assess the factor structure of this questionnaire. Patients and Methods: A principal component analysis with orthogonal (varimax) rotation was conducted on data collected from 418 patients after primary (external beam radiotherapy and permanent iodine-125 brachytherapy) and postoperative radiotherapy for prostate cancer. Results: Health-related quality of life scores well demonstrated differences in subpopulations before radiotherapy and different toxicity profiles of specific radiotherapy concepts. The extraction of 12 factors accounted for 75.5% of the variance. With exception of the sexual domain, a strong dependence between the function in a domain and the related bother was found. The concept to discriminate urinary incontinence and urinary irritation/ obstruction subscales was supported. However, the items ‘bleeding with urination’ and ‘bloody stools’ have loaded on separate factors. After separation of the items of the function and bother subscales, a 4-factor solution was confirmed to be optimal, respectively. Conclusion: The obtained factor structure corresponds to the original Expanded Prostate Cancer Index Composite subscales. Minor divergences have been found, depicting especially items concerning ‘incontinence’ and ‘bleeding’ as distinct aspects of a domain.

© 2008 S. Karger AG, Basel


  

Author Contacts

Michael Pinkawa, MD, PhD, Department of Radiation Oncology, RWTH Aachen University, Pauwelsstrasse 30, DE–52057 Aachen (Germany), Tel. +49 241 80 35314, Fax +49 241 80 82543, E-Mail MPinkawa@ukaachen.de

  

Article Information

Received: September 5, 2008
Accepted: October 31, 2008
Published online: January 7, 2009
Number of Print Pages : 8

  

Publication Details

Current Urology (International Journal of Shandong University)

Vol. 2, No. 3, Year 2008 (Cover Date: January 2009)

Journal Editor: Zhao S. (Jinan), Ekman P. (Stockholm)
ISSN: 1661-7649 (Print), eISSN: 1661-7657 (Online)

For additional information: http://www.karger.com/CUR


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 9/5/2008
Accepted: 10/31/2008
Published online: 1/7/2009
Issue release date: January 2009

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 1661-7649 (Print)
eISSN: 1661-7657 (Online)

For additional information: http://www.karger.com/CUR


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.