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Original Paper

Diffusion Tensor Imaging of the Subcortical Auditory Tract in Subjects with Long-Term Unilateral Sensorineural Hearing Loss

Wu C.-M.a · Ng S.-H.b, c · Liu T.-C.d

Author affiliations

aDepartment of Otolaryngology, Chang-Gang Memorial Hospital, College of Medicine, Chang-Gang University, bDepartment of Diagnostic Radiology, Chang-Gung Memorial Hospital, cDepartment of Medical Imaging and Radiological Sciences, Chang-Gung University, Linkou, and dDepartment of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan

Related Articles for ""

Audiol Neurotol 2009;14:248–253

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: June 27, 2008
Accepted: October 13, 2008
Published online: January 15, 2009
Issue release date: May 2009

Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 3

ISSN: 1420-3030 (Print)
eISSN: 1421-9700 (Online)

For additional information: http://www.karger.com/AUD

Abstract

Several indices including axial diffusivity (λII), radial diffusivity (λ·), mean diffusivity, and fractional anisotropy (FA) along the auditory pathway were extracted from diffusion tensor magnetic resonance images in 19 patients with unilateral sensorineural hearing loss (SNHL). Two regions of interest were selected bilaterally for evaluation: the lateral lemniscus and inferior colliculus. A significant decrease was observed in FA on the contralateral side in patients with SNHL due to an increase in λII while λ· remained unchanged. Although the orientation of neural fibers along the subcortical auditory pathway appeared to be intact, the reduction in FA and increase in λ· on the contralateral side might be attributed to axonal loss and/or demyelination.

© 2009 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: June 27, 2008
Accepted: October 13, 2008
Published online: January 15, 2009
Issue release date: May 2009

Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 3

ISSN: 1420-3030 (Print)
eISSN: 1421-9700 (Online)

For additional information: http://www.karger.com/AUD


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