Diffusion Tensor Imaging of the Subcortical Auditory Tract in Subjects with Long-Term Unilateral Sensorineural Hearing LossWu C.-M.a · Ng S.-H.b, c · Liu T.-C.d
aDepartment of Otolaryngology, Chang-Gang Memorial Hospital, College of Medicine, Chang-Gang University, bDepartment of Diagnostic Radiology, Chang-Gung Memorial Hospital, cDepartment of Medical Imaging and Radiological Sciences, Chang-Gung University, Linkou, and dDepartment of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan
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Article / Publication Details
Several indices including axial diffusivity (λII), radial diffusivity (λ·), mean diffusivity, and fractional anisotropy (FA) along the auditory pathway were extracted from diffusion tensor magnetic resonance images in 19 patients with unilateral sensorineural hearing loss (SNHL). Two regions of interest were selected bilaterally for evaluation: the lateral lemniscus and inferior colliculus. A significant decrease was observed in FA on the contralateral side in patients with SNHL due to an increase in λII while λ· remained unchanged. Although the orientation of neural fibers along the subcortical auditory pathway appeared to be intact, the reduction in FA and increase in λ· on the contralateral side might be attributed to axonal loss and/or demyelination.
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