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Vol. 63, No. 2, 1996
Issue release date: 1996
Respiration 1996;63:61–65
Original Paper

Severe Community-Acquired Pneumonia: A Possible Role for Chlamydia pneumoniae

Cosentini R.a · Blasi F.b · Raccanelli R.b · Rossi S.a · Arosio C.a · Tarsia P.b · Randazzo A.a · Allegro L.b
aDepartment of Emergency Medicine, Ospedale Maggiore and bInstitute of Respiratory Diseases, University of Milan, Italy


Between July 1992 and June 1993, 61 patients with severe community-acquired pneumonia were admitted to our semi-intensive care unit. For all patients chest X-ray, blood gas analysis while breathing room air, Gram stain and culture of bronchoaspirate, determination of acute and convalescent antibody titers for Legionella pneumophila, Mycoplasma pneumoniae and Chlamydia pneumoniae, blood culture when body temperature was greater than 38 °C, and pharyngeal swab for C. pneumoniae detection by means of an indirect immunofluorescence test were obtained. Among the patients enrolled, 15 suffered from chronic obstructive pulmonary disease, 18 had serious chronic diseases, 9 were immunodeficient and 15 had cardiovascular diseases, and only 4 had no underlying disease. Etiologic diagnosis was reached in 30 cases (49%). As expected, due to the high rate of seriously ill patients, gram-negative pathogens were identified most commonly (15%), followed by Streptococcus pneumoniae (10%) and, surprisingly, by C pneumoniae (10%). These data, showing the possible emergence of Pseudomonas aeruginosa and C pneumoniae, warrant further studies in order to verify whether the epidemiological pattern of severe community-acquired pneumonia is actually changing.

 goto top of outline Author Contacts

Dott. Francesco Blasi, Istituto di Tisiologia e Malattie dell’Apparato Respiratorio, University; degli Studi di Milano, Ospedale Maggiore di Milano, via F. Sforza, 35, I-20122 Milano (Italy)

 goto top of outline Article Information

Received: December 29, 1994
Accepted after revision: July 19, 1995
Published online: January 21, 2009
Number of Print Pages : 5

 goto top of outline Publication Details

Respiration (International Journal of Thoracic Medicine)

Vol. 63, No. 2, Year 1996 (Cover Date: 1996)

Journal Editor: Bolliger C.T. (Cape Town)
ISSN: 0025-7931 (Print), eISSN: 1423-0356 (Online)

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