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Table of Contents
Vol. 15, No. 4, 1977
Issue release date: 1977
Section title: First International Symposium and HLA Disease
Digestion 1977;15:260–270
(DOI:10.1159/000198011)

HLA in Different Forms of Chronic Active Hepatitis A Comparison between Adult Patients and Children

Freudenberg J. · Baumann H. · Arnold W. · Berger J. · Meyer zum Büschenfelde K.-H.
II. Medizinische Universitätsklinik und Poliklinik, Universitätskinderklinik, Institut für Medizinische Statistik und Dokumentation der Johannes-Gutenberg-Universität, Mainz

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Article / Publication Details

First-Page Preview
Abstract of First International Symposium and HLA Disease

Received: August 03, 1976
Accepted: September 02, 1976
Published online: January 27, 2009
Issue release date: 1977

Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG

Abstract

108 adult patients and 34 children with chronic active hepatitis (CAH) are divided in four groups on the basis of presence and absence of hepatitis B surface antigen (HBsAg) and autoantibodies (AutoAb). There are significant differences in the numeric distribution among the four groups and the sex distribution between adult patients and children, but no differences in the frequencies of the HLA antigens tested. An increased frequency of HLA-B8 (and HLA-Al) compared with normal controls and the other groups is only found in autoimmune types of CAH, characterized as HBsAg-negative, AutoAb-positive CAH. HBsAg-negative, AutoAb-negative forms of CAH are called cryptogenic CAH and these are most likely non-hepatitis B virus induced types of CAH. In these and hepatitis B virus induced forms of CAH no significant deviation of any HLA antigen tested could be found.

© 1977 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of First International Symposium and HLA Disease

Received: August 03, 1976
Accepted: September 02, 1976
Published online: January 27, 2009
Issue release date: 1977

Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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