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Vol. 30, No. 3, 1984
Issue release date: 1984
Section title: Original Paper
Digestion 1984;30:158–164
(DOI:10.1159/000199100)

Immunolocalization of Collagen Types, Laminin and Fibronectin in the Normal Human Pancreas

Uscanga L. · Kennedy R.H. · Stocker S. · Grimaud J.-A. · Sarles H.
Inserm U31 Marseille, France; CNRS-ERA 819, Institut Pasteur, Lyon, France

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 1/30/1984
Accepted: 3/28/1984
Published online: 1/28/2009
Issue release date: 1984

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG

Abstract

In order to define the connective matrix organization of the normal human pancreas collagen types I, III, pro-Ill and IV, laminin and fibronectin were labeled using specific, antihuman antibodies. Visualization was by indirect immunofluorescence. Collagen types I, III and pro-Ill were present within lobules: around acini, ducts and small vessels. Their immunofluorescence reaction was particularly obvious in septa and it also outlined interlobular vessels and ducts. The type III and pro-Ill fractions possessed a characteristic, branched appearance in many situations, when compared to the more linear type I reaction. Collagen type IV, laminin and fibronectin were closely applied to acini, ducts and vessels, but in contrast to the other collagen types were absent from septa.

© 1984 S. Karger AG, Basel


  

Author Contacts

R.H. Kennedy, INSERM U31, 46, boulevard de la Gaye, F-13009 Marseille (France)

  

Article Information

Received: January 30, 1984
Accepted: March 28, 1984
Published online: January 28, 2009
Number of Print Pages : 7

  

Publication Details

Digestion (International Journal of Gastroenterology)

Vol. 30, No. 3, Year 1984 (Cover Date: 1984)

Journal Editor: Beglinger C. (Basel), Göke B. (Munich)
ISSN: 0012-2823 (Print), eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 1/30/1984
Accepted: 3/28/1984
Published online: 1/28/2009
Issue release date: 1984

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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