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Vol. 31, No. 1, 1985
Issue release date: 1985
Digestion 1985;31:54–59
Case Report

A Metastatic Endocrine-Neurogenic Tumor of the Ampulla of Vater with Multiple Endocrine Immunoreaction Malignant Paraganglioma?

Büchler M. · Malfertheiner P. · Baczako K. · Krautzberger W. · Beger H.G.
Departments of Surgery, Internal Medicine and Pathology, University of Ulm, FRG


The present case report demonstrates the history of a 50-year-old man with a mixed endocrine-neurogenous tumor of the ampulla of Vater. The tumor was localized endo-scopically after an attack of melena. There were no signs of endocrinopathy. A local resection with suturing of the pancreatic duct was performed. Morphologically, there were two different tissue types (neurogenous and carcinoid-like) with numerous cells and nerve fibers reacting immunohistochemically with somatostatin and neurotensin antisera: some immunoreactivity to PP-antibodies was observed. Still, after 20 months, the patient seems to have been cured by local resection.

 goto top of outline Author Contacts

M. Büchler, MD, Department of Surgery, University of Ulm, Steinhövelstrasse 9, D-7900 Ulm (FRG)

 goto top of outline Article Information

Received: January 1, 1984
Received in revised form: June 28, 1984
Published online: January 28, 2009
Number of Print Pages : 6

 goto top of outline Publication Details

Digestion (International Journal of Gastroenterology)

Vol. 31, No. 1, Year 1985 (Cover Date: 1985)

Journal Editor: Beglinger C. (Basel), Göke B. (Munich)
ISSN: 0012-2823 (Print), eISSN: 1421-9867 (Online)

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