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Vol. 27, Suppl. 1, 2009
Issue release date: April 2009
Section title: Etiology and Risk Factors for Ischemic Stroke
Cerebrovasc Dis 2009;27(suppl 1):104–110
(DOI:10.1159/000200447)

Sleep-Disordered Breathing and Acute Stroke

Cardona Portela P. · Campdelacreu Fumadó J. · Quesada García H. · Rubio Borrego F.
aStroke Unit, bDepartment of Neurology, Hospital Universitario de Bellvitge, Barcelona, Spain

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Article / Publication Details

First-Page Preview
Abstract of Etiology and Risk Factors for Ischemic Stroke

Published online: 4/3/2009

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 0

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED

Abstract

Background: Sleep-disordered breathing (SDB) is a disease of increasing importance and it is frequent in stroke patients. SDB is being recognized as an independent risk factor for several clinical consequences, including cardiovascular and cerebrovascular disease. Methods: The present review summarizes the current evidence for an independent association between SDB and stroke, defining SDB subgroups, mechanisms, confounding factors and other epidemiological aspects. We analyze stroke outcome and prognosis in SDB patients. A search for recent data on this issue was made in several population-based studies and reference lists of articles. Results: Many recent studies have shown an association between SDB and stroke. Moreover, there is a high prevalence of sleep apnea in patients with stroke. The pathogenesis of stroke in obstructive sleep apnea syndrome is not completely understood and likely to be multifactorial. Several mechanisms like hemodynamic disturbances and inflammatory or endothelial dysfunction could be involved. The presence of SDB in stroke patients may lead to a poor outcome and recurrence. Noninvasive treatments such as continuous positive airway pressure may decrease the risk of stroke in terms of secondary, and possibly, primary prevention. Conclusions: SDB is associated with cerebrovascular morbidity and an unfavorable clinical course. The presence of SDB should be systematically screened in patients with acute stroke. Further studies are needed to determine whether continuous positive airway pressure treatment ameliorates stroke outcome and prognosis.


  

Author Contacts

Dr. Pedro Cardona Portela
Bellvitge University Hospital, Department of Neurology
Av. Feixa Llarga s/n., Hospitalet de Llobregat
ES–08903 Barcelona (Spain)
Tel. +34 93 607 711, Fax +34 93 2607 882, E-Mail 34109pcp@comb.es

  

Article Information

Published online: April 3, 2009
Number of Print Pages : 7
Number of Figures : 1, Number of Tables : 0, Number of References : 61

  

Publication Details

Cerebrovascular Diseases

Vol. 27, No. Suppl. 1, Year 2009 (Cover Date: April 2009)

Journal Editor: Hennerici M.G. (Mannheim)
ISSN: 1015-9770 (Print), eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED


Article / Publication Details

First-Page Preview
Abstract of Etiology and Risk Factors for Ischemic Stroke

Published online: 4/3/2009

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 0

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED


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