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Table of Contents
Vol. 54, No. 2, 1993
Issue release date: 1993
Section title: Review
Digestion 1993;54:65–72
(DOI:10.1159/000201015)

Vagal Regulation of Gastric Function Involves Thyrotropin Releasing Hormone in the Medullary Raphe Nuclei and Dorsal Vagal Complex

Taché Y.a · Yang H.a · Yoneda M.b
aCURE/UCLA Digestive Disease Center, VA Wadsworth Medical Center, Department of Medicine and Brain Research Institute, UCLA, Los Angeles, Calif., USA; bSecond Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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Article / Publication Details

First-Page Preview
Abstract of Review

Received: 2/1/1993
Accepted: 2/24/1993
Published online: 2/5/2009
Issue release date: 1993

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG

Abstract

There is convincing electrophysiological, neuroanatomical and functional data in support of an excitatory action of thyrotropin-releasing hormone (TRH) on the dorsal motor nucleus of the vagus neurons leading to stimulation of vagal outflow to the stomach and to a vagal cholinergic-dependent stimulation of gastric secretory and motor function and alterations of mucosal integrity in rats and cats. The raphe pallidus and obscurus have become important medullary nuclei regulating vagal function through their TRH and serotonin projections to the dorsal vagal complex. However, still little is known about the transmitters and conditions which influence the activity of these TRH-containing medullary raphe neurons. Existing knowledge points out a possible physiological role of TRH in mediating vagal reflex and the cephalic phase of digestion.

© 1993 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Review

Received: 2/1/1993
Accepted: 2/24/1993
Published online: 2/5/2009
Issue release date: 1993

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG


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